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天然存在的脱氢松柏基葡糖苷的细胞分裂促进活性:细胞壁成分控制细胞分裂吗?

Cell division promoting activity of naturally occurring dehydrodiconiferyl glucosides: do cell wall components control cell division?

作者信息

Binns A N, Chen R H, Wood H N, Lynn D G

出版信息

Proc Natl Acad Sci U S A. 1987 Feb;84(4):980-4. doi: 10.1073/pnas.84.4.980.

DOI:10.1073/pnas.84.4.980
PMID:3469655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC304345/
Abstract

Naturally occurring isomers of the dehydrodiconiferyl glucosides have been isolated from Vinca rosea crown gall tumors and have been tested for cell division promoting activities in the tobacco pith and leaf assay systems. The enantiomeric isomers A and B are active, although they are required at concentrations up to 2 orders of magnitude higher than zeatin riboside to promote comparable growth. We estimate that the active dehydrodiconiferyl glucosides are present in rapidly growing tissues (tumor tissue, habituated tissue, cultured nontransformed tissue) in micromolar concentrations. In quiescent tobacco pith tissue, the levels of these compounds are reduced by a factor of 100. These results suggest that cytokinin may exert control of cell division through the accumulation of molecules (the dehydrodiconiferyl glucosides) that are apparent cell wall components.

摘要

脱氢二松柏醇葡萄糖苷的天然异构体已从长春花冠瘿瘤中分离出来,并在烟草髓和叶片检测系统中测试了其促进细胞分裂的活性。对映体异构体A和B具有活性,尽管促进可比生长所需的浓度比玉米素核苷高2个数量级。我们估计,活性脱氢二松柏醇葡萄糖苷以微摩尔浓度存在于快速生长的组织(肿瘤组织、驯化组织、培养的未转化组织)中。在静止的烟草髓组织中,这些化合物的水平降低了100倍。这些结果表明,细胞分裂素可能通过明显作为细胞壁成分的分子(脱氢二松柏醇葡萄糖苷)的积累来控制细胞分裂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd8/304345/f34d1021147d/pnas00269-0089-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd8/304345/f34d1021147d/pnas00269-0089-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd8/304345/f34d1021147d/pnas00269-0089-a.jpg

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