暴露于SV40的仓鼠胚胎细胞系中的病毒特异性核酸：与S和T抗原的相关性。
Virus-specific nucleic acids in SV40-exposed hamster embryo cell lines: correlation with S and T antigens.
作者信息
Levin M J, Oxman M N, Diamandopoulos G T, Levine A S, Henry P H, Enders J F
出版信息
Proc Natl Acad Sci U S A. 1969 Feb;62(2):589-96. doi: 10.1073/pnas.62.2.589.
Abstract
A number of homologous SV40-exposed hamster embryonic cell lines were examined for the presence of RNA complementary to SV40 DNA. Only those lines containing the SV40 T antigen were found to have such virus-specific RNA. In lines containing the SV40 S antigen, but not the SV40 T antigen, virus-specific RNA was not detected. These findings suggest that the S antigen is not coded for directly by the SV40 genome.
摘要
对一些暴露于SV40的同源仓鼠胚胎细胞系进行了检测，以确定是否存在与SV40 DNA互补的RNA。结果发现，只有那些含有SV40 T抗原的细胞系才有这种病毒特异性RNA。在含有SV40 S抗原但不含有SV40 T抗原的细胞系中，未检测到病毒特异性RNA。这些发现表明，S抗原不是由SV40基因组直接编码的。
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