Aaronson S A, Parks W P, Scolnick E M, Todaro G J
Proc Natl Acad Sci U S A. 1971 May;68(5):920-4. doi: 10.1073/pnas.68.5.920.
Sera from rats bearing transplantable tumors induced by murine C-type tumor viruses contain an inhibitor of the activity of the viral RNA-dependent DNA polymerase. The inhibitor is shown to be an immunoglobulin (IgG) directed against the enzyme. Antiserum made in rabbits against partially purified murine leukemia virus polymerase also inhibits the polymerases of other mammalian C-type RNA-containing tumor viruses. Thus, the polymerases from different mammalian tumor viruses are antigenically related.
携带由鼠C型肿瘤病毒诱导的可移植肿瘤的大鼠血清中含有一种病毒RNA依赖性DNA聚合酶活性的抑制剂。已证明该抑制剂是一种针对该酶的免疫球蛋白（IgG）。用兔制备的针对部分纯化的鼠白血病病毒聚合酶的抗血清也能抑制其他含C型RNA的哺乳动物肿瘤病毒的聚合酶。因此，来自不同哺乳动物肿瘤病毒的聚合酶在抗原性上相关。
