细胞培养物对石棉纤维的反应。
Response of cell cultures to asbestos fibers.
作者信息
Bruch J
出版信息
Environ Health Perspect. 1974 Dec;9:253-4. doi: 10.1289/ehp.749253.
Abstract
The reaction of macrophages to asbestos and glass fibers was studied by light and by electron microscopy. Measurements were made of LDH release, staining with erythrosine B, and lactate production. Size and shape of asbestos fibers were found to have more effect than the physicochemical properties of the surface. Long fibers resulted in a protracted pathogenic but no acute cytotoxic effect.
摘要
通过光学显微镜和电子显微镜研究了巨噬细胞对石棉纤维和玻璃纤维的反应。进行了乳酸脱氢酶释放量、赤藓红B染色和乳酸生成量的测定。发现石棉纤维的尺寸和形状比其表面的物理化学性质影响更大。长纤维会导致持久的致病性，但没有急性细胞毒性作用。
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