择期手术后的总甲状腺激素和游离甲状腺激素浓度。
Total and free thyroid hormone concentrations after elective surgery.
作者信息
Prescott R W, Yeo P P, Watson M J, Johnston I D, Ratcliffe J G, Evered D C
出版信息
J Clin Pathol. 1979 Apr;32(4):321-4. doi: 10.1136/jcp.32.4.321.
Abstract
Changes in thyroid hormone concentration and distribution and plasma cortisol levels have been followed in 11 patients undergoing elective cholocystectomy. A significant rise in total and free thyroxine (T4) and fall in total and free triiodothyronine (T3) were noted after surgery. Reverse T3 concentrations rose substantially, suggesting that peripheral conversion of T4 to T3 is diminished and that there is preferential formation of reverse T3. Serum thyroid stimulating hormone concentrations did not change. There was no direct correlation between the change in cortisol and the change in thyroid hormone or reverse T3 concentrations.
摘要
对11例接受择期胆囊切除术的患者，监测了甲状腺激素浓度和分布以及血浆皮质醇水平的变化。术后发现总甲状腺素（T4）和游离甲状腺素显著升高，总三碘甲状腺原氨酸（T3）和游离三碘甲状腺原氨酸降低。反式T3浓度大幅上升，提示T4向T3的外周转化减少，且反式T3优先生成。血清促甲状腺激素浓度未发生变化。皮质醇变化与甲状腺激素或反式T3浓度变化之间无直接相关性。
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