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β-半乳糖苷酶无义片段的基因与降解

The Gene and Degradation of β-Galactosidase Nonsense Fragments.

作者信息

Shineberg B, Zipser D

出版信息

J Bacteriol. 1973 Dec;116(3):1469-71. doi: 10.1128/jb.116.3.1469-1471.1973.

DOI:10.1128/jb.116.3.1469-1471.1973
PMID:4584816
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC246507/
Abstract

N-terminal beta-galactosidase fragments are rapidly degraded in growing cells of Escherichia coli. Mutations in the lon gene are sufficient to enhance the stability of these polypeptides.

摘要

N端β-半乳糖苷酶片段在大肠杆菌生长细胞中迅速降解。lon基因中的突变足以增强这些多肽的稳定性。

相似文献

1
The Gene and Degradation of β-Galactosidase Nonsense Fragments.β-半乳糖苷酶无义片段的基因与降解
J Bacteriol. 1973 Dec;116(3):1469-71. doi: 10.1128/jb.116.3.1469-1471.1973.
2
Isolating tryptophan regulatory mutants in Escherichia coli by using a trp-lac fusion strain.利用色氨酸-乳糖操纵子融合菌株筛选大肠杆菌中的色氨酸调控突变体。
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Mutants of Escherichia coli with a defect in the degradation of nonsense fragments.在无义片段降解方面存在缺陷的大肠杆菌突变体。
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4
Deg phenotype of Escherichia coli lon mutants.大肠杆菌lon突变体的Deg表型
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Ultraviolet light sensitivity of Escherichia coli K-12 strains carrying ruv mutations in combination with uvrA or lon mutant alleles.携带ruv突变并与uvrA或lon突变等位基因相结合的大肠杆菌K-12菌株对紫外线的敏感性。
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Second naturally occurring beta-galactosidase in E. coli.大肠杆菌中第二种天然存在的β-半乳糖苷酶。
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Dominant mutations (lex) in Escherichia coli K-12 which affect radiation sensitivity and frequency of ultraviolet lght-induced mutations.大肠杆菌K-12中影响辐射敏感性和紫外线诱导突变频率的显性突变（lex）
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[A genetic study of the lon-mutants of E. coli K-12].[大肠杆菌K-12 lon突变体的遗传学研究]
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Isolation and characterization of an Escherichia coli K-12 mutant with a temperature-sensitive recA- phenotype.一株具有温度敏感型recA-表型的大肠杆菌K-12突变体的分离与鉴定。
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[Revertants of recA-strains of Escherichia coli K-12].[大肠杆菌K-12 recA菌株的回复突变体]
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Identification of the gene lon (capR) product as a 94-kilodalton polypeptide by cloning and deletion analysis.通过克隆和缺失分析鉴定基因lon（capR）产物为一种94千道尔顿的多肽。
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本文引用的文献

1
ANALYSIS OF A GENE CONTROLLING CELL DIVISION AND SENSITIVITY TO RADIATION IN ESCHERICHIA COLI.大肠杆菌中一个控制细胞分裂及辐射敏感性的基因分析
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A LOCUS THAT CONTROLS FILAMENT FORMATION AND SENSITIVITY TO RADIATION IN ESCHERICHIA COLI K-12.一个控制大肠杆菌K-12中丝状形成和对辐射敏感性的基因座。
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REGULATORY MECHANISMS FOR SYNTHESIS OF CAPSULAR POLYSACCHARIDE IN MUCOID MUTANTS OF ESCHERICHIA COLI K12.大肠杆菌K12黏液突变体中荚膜多糖合成的调控机制
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Suppression of radiation sensitivity and capsular polysaccharide synthesis in Escherichia coli K-12 by ochre suppressors.赭石抑制基因对大肠杆菌K-12辐射敏感性和荚膜多糖合成的抑制作用
J Bacteriol. 1967 Aug;94(2):388-95. doi: 10.1128/jb.94.2.388-395.1967.
5
A regulator gene that is dominant on an episome and recessive on a chromosome.一种调节基因，它在附加体上是显性的，而在染色体上是隐性的。
Proc Natl Acad Sci U S A. 1965 Oct;54(4):1084-91. doi: 10.1073/pnas.54.4.1084.
6
Bacterial mutants defective in plasmid formation: requirement for the lon + allele.质粒形成缺陷的细菌突变体：lon + 等位基因的需求
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1469-73. doi: 10.1073/pnas.68.7.1469.
7
In vivo degradation of nonsense fragments in E. coli.大肠杆菌中无义片段的体内降解
Nature. 1970 Dec 19;228(5277):1151-4. doi: 10.1038/2281151a0.
8
Polypeptide products of nonsense mutations. I. Termination fragments from nonsense mutations in the Z gene of the lac operon of Escherichia coli.无义突变的多肽产物。I. 大肠杆菌乳糖操纵子Z基因无义突变产生的终止片段。
J Mol Biol. 1970 Jun 14;50(2):359-71. doi: 10.1016/0022-2836(70)90198-1.
9
Depression of guanosine diphosphate-mannose pyrophosphorylase by mutations in two different regulator genes involved in capsular polysaccharide synthesis in Escherichia coli K-12.大肠杆菌K-12中参与荚膜多糖合成的两个不同调节基因突变导致鸟苷二磷酸甘露糖焦磷酸化酶活性降低。
J Bacteriol. 1970 Mar;101(3):965-72. doi: 10.1128/jb.101.3.965-972.1970.
10
P1-mediated transduction of a gene that controls radiation sensitivity and capsular polysaccharide synthesis from Shigella dysenteriae to Escherichia coli.P1介导的从痢疾志贺氏菌到大肠杆菌的一个控制辐射敏感性和荚膜多糖合成的基因的转导。
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