Dordoni B, Willson R A, Thompson R P, Williams R
Br Med J. 1973 Jul 14;3(5871):86-7. doi: 10.1136/bmj.3.5871.86.
The absorption of an oral 2-g dose of paracetamol was markedly reduced by the simultaneous oral administration of either activated charcoal or cholestyramine but was only slightly reduced when the adsorbents were given 60 minutes after the paracetamol. Since the absorption of a larger dose of the drug will probably be slow, the administration of adsorbents may be of value even when delayed several hours.
同时口服活性炭或考来烯胺可显著降低口服2克对乙酰氨基酚的吸收,但在对乙酰氨基酚给药60分钟后给予吸附剂时,吸收仅略有降低。由于较大剂量药物的吸收可能较慢,即使延迟数小时给药,吸附剂的使用可能仍有价值。