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辛德毕斯病毒的糖蛋白:寡糖的初步表征

Glycoproteins of Sindbis virus: priliminary characterization of the oligosaccharides.

作者信息

Sefton B M, Keegstra K

出版信息

J Virol. 1974 Sep;14(3):522-30. doi: 10.1128/JVI.14.3.522-530.1974.

Abstract

The carbohydrate content of Sindbis virus was determined by gas chromatographic analysis. The two viral glycoproteins were found to be approximately 8% carbohydrate by weight. Mannose is the sugar present in the largest amount. Smaller amounts of glucosamine, galactose, sialic acid, and fucose were also detected. Each of the two viral glycoproteins appears to contain two structurally unrelated oligosaccharides. Two of the three Sindbis-specific glycoproteins found in infected chick cells were shown to contain short, unfinished oligosaccharides.

摘要

通过气相色谱分析测定了辛德毕斯病毒的碳水化合物含量。发现这两种病毒糖蛋白的碳水化合物重量约为8%。甘露糖是含量最多的糖类。还检测到少量的氨基葡萄糖、半乳糖、唾液酸和岩藻糖。这两种病毒糖蛋白似乎都含有两种结构不相关的寡糖。在受感染的鸡细胞中发现的三种辛德毕斯特异性糖蛋白中的两种含有短的、未完成的寡糖。

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引用本文的文献

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THE ORIGIN OF THE PROTEIN OF SINDBIS VIRUS.辛德毕斯病毒蛋白质的起源
Virology. 1964 Jun;23:217-23. doi: 10.1016/0042-6822(64)90285-5.
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Glycopeptides of the membrane glycoprotein of Sindbis virus.辛德毕斯病毒膜糖蛋白的糖肽
J Mol Biol. 1970 Feb 14;47(3):449-66. doi: 10.1016/0022-2836(70)90314-1.
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Biosynthesis of the Sindbis virus carbohydrates.辛德毕斯病毒碳水化合物的生物合成。
J Virol. 1973 Dec;12(6):1366-74. doi: 10.1128/JVI.12.6.1366-1374.1973.

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