啮齿动物或人类肝脏组织产生的卤代乙烯、氯丁二烯和二氯丁烯的诱变和烷基化代谢产物。细胞色素P450相关微粒体单加氧酶形成环氧乙烷的证据。 - Suppr

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Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases.

作者信息

Bartsch H, Malaveille C, Barbin A, Planche G

出版信息

Arch Toxicol. 1979 Feb 23;41(4):249-77. doi: 10.1007/BF00296896.

DOI:10.1007/BF00296896

PMID:373707

Abstract

摘要

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本文引用的文献

METABOLISM OF DISULFIRAM AND DIETHYLDITHIOCARBAMATE IN RATS WITH DEMONSTRATION OF AN IN VIVO ETHANOL-INDUCED INHIBITION OF THE GLUCURONIC ACID CONJUGATION OF THE THIOL.

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