Charnay P, Mandart E, Hampe A, Fitoussi F, Tiollais P, Galibert F
Nucleic Acids Res. 1979 Sep 25;7(2):335-46. doi: 10.1093/nar/7.2.335.
The structural gene coding for both polypeptides I and II which are the two major polypeptides of the Hepatitis B surface antigen, is found to be localized on the viral genome. This gene, referred to as gene S, is located in the partially single stranded region. It maps between positions 73.6 and 95.1% of the genome length. It is composed of 678 nucleotides, which correspond to a theoretical polypeptide of 25,422 molecular weight.
编码乙型肝炎表面抗原的两种主要多肽即多肽I和多肽II的结构基因,被发现定位于病毒基因组上。这个基因,称为基因S,位于部分单链区域。它定位在基因组长度的73.6%至95.1%之间。它由678个核苷酸组成,相当于一个理论分子量为25422的多肽。