苦瓜凝集素及其他血凝素对体外蛋白质合成的抑制作用。
Inhibition of protein synthesis in vitro by a lectin from Momordica charantia and by other haemagglutinins.
作者信息
Barbieri L, Lorenzoni E, Stirpe F
出版信息
Biochem J. 1979 Aug 15;182(2):633-5. doi: 10.1042/bj1820633.
Abstract
Protein synthesis by a rabbit reticulocyte lysate is inhibited by the haemagglutinating lectins from Momordica charantia and Crotalaria juncea seeds and from the roe of Rutilus rutilus, and by a commercial preparation of the mitogenic lectin from Phytolacca americana. The haemagglutinins from the seeds of Ricinus communis and of Vicia cracca acquired inhibitory activity after their reduction with 2-mercaptoethanol.
摘要
苦瓜种子、猪屎豆种子和拟鲤鱼籽中的血凝素以及商购的美洲商陆促有丝分裂凝集素均可抑制兔网织红细胞裂解物的蛋白质合成。蓖麻籽和广布野豌豆种子中的血凝素在用2-巯基乙醇还原后获得了抑制活性。
相似文献
1
Inhibition of protein synthesis in vitro by a lectin from Momordica charantia and by other haemagglutinins.苦瓜凝集素及其他血凝素对体外蛋白质合成的抑制作用。
Biochem J. 1979 Aug 15;182(2):633-5. doi: 10.1042/bj1820633.
2
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).苦瓜种子蛋白对体外蛋白质合成的抑制作用。
Biochem J. 1980 Feb 15;186(2):443-52. doi: 10.1042/bj1860443.
3
Toxicity of Momordica charantia lectin and inhibitor for human normal and leukaemic lymphocytes.苦瓜凝集素及抑制剂对人正常淋巴细胞和白血病淋巴细胞的毒性作用
Virchows Arch B Cell Pathol Incl Mol Pathol. 1980;33(3):257-65. doi: 10.1007/BF02899186.
4
Inhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe).来自欧洲槲寄生（Viscum album L.）的一种有毒凝集素对蛋白质合成的抑制作用。
Biochem J. 1980 Sep 15;190(3):843-5. doi: 10.1042/bj1900843.
5
A cortical lectin from the oocytes of Rutilus rutilus stimulates mitogenic activity and release of soluble factors from human lymphocyte cultures and inhibits protein synthesis in a cell-free system.来自赤睛鱼卵母细胞的一种皮质凝集素可刺激人淋巴细胞培养物中的促有丝分裂活性和可溶性因子的释放，并在无细胞系统中抑制蛋白质合成。
Int J Biochem. 1991;23(1):101-5. doi: 10.1016/0020-711x(91)90015-f.
6
Ribosome inactivating protein and lectin from bitter melon (Momordica charantia) seeds: sequence comparison with related proteins.苦瓜（苦瓜属）种子中的核糖体失活蛋白和凝集素：与相关蛋白的序列比较
Biochem Biophys Res Commun. 1998 Dec 9;253(1):143-6. doi: 10.1006/bbrc.1998.9765.
7
Fluorimetric studies of the binding of Momordica charantia (bitter gourd) lectin with ligands.苦瓜凝集素与配体结合的荧光研究。
Biochem J. 1981 Apr 1;195(1):341-3. doi: 10.1042/bj1950341.
8
New method of detecting the lectin activity of Momordica charantia.检测苦瓜凝集素活性的新方法。
Vox Sang. 1990;58(4):307-8. doi: 10.1111/j.1423-0410.1990.tb05005.x.
9
Isolation and partial characterization of a lectin from Euphorbia heterophylla seeds.大戟属叶下珠种子中一种凝集素的分离及部分特性鉴定
Biochem J. 1983 Oct 1;215(1):141-5. doi: 10.1042/bj2150141.
10
Isolation and partial characterization of 3 nontoxic d-galactose-specific isolectins from seeds of Momordica balsamina.从苦瓜种子中分离并部分鉴定3种无毒的D-半乳糖特异性异凝集素。
J Mol Recognit. 2017 Feb;30(2). doi: 10.1002/jmr.2582. Epub 2016 Oct 24.
引用本文的文献
1
Effectiveness of Antihyperglycemic Effect of : Implication of T-Cell Cytokines.降糖作用的有效性：T细胞细胞因子的影响
Evid Based Complement Alternat Med. 2017;2017:3707046. doi: 10.1155/2017/3707046. Epub 2017 Nov 28.
2
Evidence of Immunosuppressive and Th2 Immune Polarizing Effects of Antidiabetic Fruit Juice.抗糖尿病果汁的免疫抑制和Th2免疫极化作用的证据。
Biomed Res Int. 2017;2017:9478048. doi: 10.1155/2017/9478048. Epub 2017 Jul 25.
3
Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.高尿酸血症、黄嘌呤氧化还原酶与植物源核糖体失活蛋白：菲奥伦佐·斯特尔佩对前沿研究的贡献
Molecules. 2017 Jan 27;22(2):206. doi: 10.3390/molecules22020206.
4
Ribosome-inactivating and related proteins.核糖体失活及相关蛋白
Toxins (Basel). 2015 May 8;7(5):1556-615. doi: 10.3390/toxins7051556.
5
A lectin from Bryonia dioica root stocks.野葛根凝集素。
Planta. 1984 Mar;160(3):222-8. doi: 10.1007/BF00402858.
6
Antileukemic Potential of Momordica charantia Seed Extracts on Human Myeloid Leukemic HL60 Cells.苦瓜籽油抗人髓性白血病 HL60 细胞的作用
Evid Based Complement Alternat Med. 2012;2012:732404. doi: 10.1155/2012/732404. Epub 2012 May 13.
7
Isolation and partial characterization of nigrin b, a non-toxic novel type 2 ribosome-inactivating protein from the bark of Sambucus nigra L.黑接骨木树皮中一种无毒新型2型核糖体失活蛋白黑接骨木蛋白b的分离与部分特性分析
Plant Mol Biol. 1993 Sep;22(6):1181-6. doi: 10.1007/BF00028990.
8
Inhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe).来自欧洲槲寄生（Viscum album L.）的一种有毒凝集素对蛋白质合成的抑制作用。
Biochem J. 1980 Sep 15;190(3):843-5. doi: 10.1042/bj1900843.
9
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).苦瓜种子蛋白对体外蛋白质合成的抑制作用。
Biochem J. 1980 Feb 15;186(2):443-52. doi: 10.1042/bj1860443.
10
Seed extracts inhibiting protein synthesis in vitro.种子提取物在体外抑制蛋白质合成。
Biochem J. 1980 Feb 15;186(2):439-41. doi: 10.1042/bj1860439.
本文引用的文献
1
Synthesis of hemoglobin in a cell-free system. I. Properties of the complete system.无细胞体系中血红蛋白的合成。I. 完整体系的性质。
J Biol Chem. 1962 Mar;237:760-7.
2
Purification of galactose-binding phytoagglutinins and phytotoxin by affinity column chromatography using sepharose.使用琼脂糖通过亲和柱色谱法纯化半乳糖结合植物凝集素和植物毒素。
Experientia. 1972 Jan 15;28(1):84-5. doi: 10.1007/BF01928278.
3
The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II.一种抗病毒肽对肽链延伸酶EF-I和EF-II核糖体反应的影响。
Arch Biochem Biophys. 1973 Apr;155(2):278-89. doi: 10.1016/0003-9861(73)90116-1.
4
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system.用β-巯基乙醇处理相思子毒素和蓖麻毒素，对它们在小鼠体内的毒性以及在无细胞系统中抑制蛋白质合成的能力产生相反的影响。
FEBS Lett. 1972 Nov 15;28(1):48-50. doi: 10.1016/0014-5793(72)80674-4.
5
The biochemistry of plant lectins (phytohemagglutinins).植物凝集素（植物血凝素）的生物化学
Annu Rev Biochem. 1973;42(0):541-74. doi: 10.1146/annurev.bi.42.070173.002545.
6
The interaction of Ricinus communis agglutinin with normal and tumor cell surfaces.蓖麻凝集素与正常细胞及肿瘤细胞表面的相互作用。
Biochim Biophys Acta. 1972 May 9;266(2):543-7. doi: 10.1016/0005-2736(72)90109-5.
7
On the surface structure of murine ascites tumors. I. Interactions with various phytoagglutinins.关于小鼠腹水瘤的表面结构。I. 与各种植物凝集素的相互作用。
Int J Cancer. 1970 Sep 15;6(2):283-9. doi: 10.1002/ijc.2910060216.
8
Purification and partial characterization of the antiviral protein from Phytolacca americana which inhibits eukaryotic protein synthesis.美洲商陆中抑制真核生物蛋白质合成的抗病毒蛋白的纯化及部分特性分析
Arch Biochem Biophys. 1975 Aug;169(2):522-8. doi: 10.1016/0003-9861(75)90195-2.
9
Inhibition of protein synthesis in vitro by crotins and ricin. Effect on the steps of peptide chain elongation.巴豆毒素和蓖麻毒素对体外蛋白质合成的抑制作用。对肽链延伸步骤的影响。
Biochem J. 1976 Apr 15;156(1):7-13. doi: 10.1042/bj1560007.
10
Studies on the proteins from the seeds of Croton tiglium and of Jatropha curcas. Toxic properties and inhibition of protein synthesis in vitro.巴豆和麻疯树种子蛋白质的研究。毒性特性及体外对蛋白质合成的抑制作用。
Biochem J. 1976 Apr 15;156(1):1-6. doi: 10.1042/bj1560001.
Zotero 插件