花生四烯酸聚集嗜中性粒细胞。
Arachidonic acid aggregates neutrophils.
作者信息
O'Flaherty J T, Showell H S, Becker E L, Ward P A
出版信息
Inflammation. 1979 Sep;3(4):431-6. doi: 10.1007/BF00913500.
PMID:511297
Abstract
Arachidonic acid, but not several structurally similar fatty acids, stimulated neutrophils in suspension to aggregate; this effect was blocked by 5, 8, 11, 14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism. Analagous to platelets, arachidonate may be a precursor of active metabolites which mediate neutrophil responses.
摘要
花生四烯酸，而非几种结构相似的脂肪酸，能刺激悬浮状态的中性粒细胞发生聚集；这种效应被花生四烯酸代谢抑制剂5,8,11,14-二十碳四炔酸所阻断。与血小板类似，花生四烯酸可能是介导中性粒细胞反应的活性代谢物的前体。
Zotero 插件