Spence K D
J Bacteriol. 1971 May;106(2):325-30. doi: 10.1128/jb.106.2.325-330.1971.
A mutant has been isolated whose aberration severely restricts the ability of cells of Saccharomyces cerevisiae to take up S-adenosylmethionine. The mutation apparently also affects adenosylhomocysteine uptake, but not that of the S-adenosylmethionine moieties adenine, homocysteine, homoserine, or methionine, nor the sulfonium compound, S-methylmethionine. It is a single, chromosomal mutation whose expression is not dependent on the presence of ammonium ions.
已分离出一种突变体,其畸变严重限制了酿酒酵母细胞摄取S-腺苷甲硫氨酸的能力。该突变显然也影响腺苷同型半胱氨酸的摄取,但不影响S-腺苷甲硫氨酸的部分腺嘌呤、同型半胱氨酸、高丝氨酸或甲硫氨酸,也不影响锍化合物S-甲基甲硫氨酸的摄取。它是一种单一的染色体突变,其表达不依赖于铵离子的存在。