X-gp70：小鼠白血病病毒包膜蛋白gp70的第三种分子形式，在小鼠淋巴细胞上表达。
X-gp70: a third molecular species of the envelope protein gp70 of murine leukemia virus, expressed on mouse lymphoid cells.
作者信息
Tung J S, Shen F W, Fleissner E, Boyse E A
出版信息
J Exp Med. 1976 Apr 1;143(4):969-74. doi: 10.1084/jem.143.4.969.
Abstract
Three variants of the gp70 envelope component of MuLV are now recognizable serologically: GIX-gp70, 0-gp70, and X-gp70. The last of these, X-gp70, has so far been found only in mice or cells producing abundant C-type virus. This distinguishes X-gp70, provisionally, from the GIX-gp70 and 0-gp70 variants, each of which can be expressed on normal thymocytes without accompanying virus production, as exemplified by mouse strains 129 and B6, respectively. The X-gp70 genotype, however, is not limited to strains of mice-producing abundant virus, because X-gp70+ leukemias occur in strains of mice which do not produce a great deal of virus and whose thymocytes and other tissues are X-gp70-; this is analogous to the appearance of GIX+ leukemias in GIX- mouse strains.
摘要
目前，通过血清学方法可识别出莫氏白血病病毒（MuLV）包膜成分gp70的三种变体：GIX-gp70、0-gp70和X-gp70。其中，X-gp70迄今为止仅在产生大量C型病毒的小鼠或细胞中发现。这暂时将X-gp70与GIX-gp70和0-gp70变体区分开来，例如，GIX-gp70和0-gp70变体分别可在129和B6小鼠品系的正常胸腺细胞上表达，且无伴随病毒产生。然而，X-gp70基因型并不局限于产生大量病毒的小鼠品系，因为在不产生大量病毒且其胸腺细胞和其他组织为X-gp70阴性的小鼠品系中会出现X-gp70阳性白血病；这类似于GIX阴性小鼠品系中出现GIX阳性白血病的情况。
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本文引用的文献
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The G-IX system. A cell surface allo-antigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome.G-IX系统。一种与鼠白血病病毒相关的细胞表面同种异体抗原；关于病毒基因组染色体整合的意义。
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Isolation and characterization of H-2 and TL alloantigens from the surface of mouse lymphocytes.从小鼠淋巴细胞表面分离并鉴定H-2和TL同种异体抗原。
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Leukemia-associated transplantation antigens related to murine leukemia virus. The X.1 system: immune response controlled by a locus linked to H-2.与鼠白血病病毒相关的白血病相关移植抗原。X.1系统：由与H-2连锁的基因座控制的免疫反应。
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Diversity of envelope antigens on murine type-C RNA viruses.小鼠C型RNA病毒包膜抗原的多样性。
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Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses.自然发生的鼠白血病病毒诱导的白血病抗原：它们与粗病毒及其他鼠白血病病毒抗原的关系。
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Editorial: Murine type-C RNA viruses: a proposed reclassification, other possible pathogenicities, and a new immunologic function.
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