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相似文献

1
X-gp70: a third molecular species of the envelope protein gp70 of murine leukemia virus, expressed on mouse lymphoid cells.X-gp70：小鼠白血病病毒包膜蛋白gp70的第三种分子形式，在小鼠淋巴细胞上表达。
J Exp Med. 1976 Apr 1;143(4):969-74. doi: 10.1084/jem.143.4.969.
2
Relation of gp70 to spontaneous cytolytic activity of mouse spleen cells.gp70与小鼠脾细胞自发细胞溶解活性的关系。
Immunogenetics. 1981;12(1-2):153-9. doi: 10.1007/BF01561658.
3
Cellular expression of murine leukemia virus gp70-related antigen on thymocytes of uninfected mice correlates with Fv-4 gene-controlled resistance to Friend leukemia virus infection.未感染小鼠胸腺细胞上鼠白血病病毒gp70相关抗原的细胞表达与Fv-4基因控制的对Friend白血病病毒感染的抗性相关。
Virology. 1983 Jul 15;128(1):127-39. doi: 10.1016/0042-6822(83)90324-0.
4
Spontaneous autoimmunization to GIX cell surface antigen in hybrid mice.杂交小鼠中对GIX细胞表面抗原的自发自身免疫
J Exp Med. 1976 Aug 1;144(2):533-42. doi: 10.1084/jem.144.2.533.
5
Relation of GIX antigen of thymocytes to envelope glycoprotein of murine leukemia virus.胸腺细胞的GIX抗原与鼠白血病病毒包膜糖蛋白的关系。
J Exp Med. 1975 Jan 1;141(1):188-97. doi: 10.1084/jem.141.1.188.
6
Influence of Fv-1 alleles on cellular expression of gp70.Fv-1等位基因对gp70细胞表达的影响。
J Exp Med. 1980 Apr 1;151(4):980-3. doi: 10.1084/jem.151.4.980.
7
Age-related changes in cell surface antigens of preleukemic AKR thymocytes.白血病前期AKR胸腺细胞表面抗原的年龄相关变化。
J Exp Med. 1976 Jul 1;144(1):193-208. doi: 10.1084/jem.144.1.193.
8
A cell surface antigen of the mouse related to xenotropic MuLv defined by naturally occurring antibody and monoclonal antibody. Relation to Gix G(rada1), G(aksl2) systems of MuLV-related antigens.一种由天然存在的抗体和单克隆抗体所定义的、与嗜异源性小鼠白血病病毒（MuLv）相关的小鼠细胞表面抗原。与MuLv相关抗原的Gix G(rada1)、G(aksl2)系统的关系。
J Exp Med. 1981 Sep 1;154(3):659-75. doi: 10.1084/jem.154.3.659.
9
G(RADA1): a new cell surface antigen of mouse leukemia defined by naturally occurring antibody and its relationship to murine leukemia virus.G(RADA1)：一种由天然存在的抗体所定义的小鼠白血病新细胞表面抗原及其与鼠白血病病毒的关系。
J Exp Med. 1978 Apr 1;147(4):1089-105. doi: 10.1084/jem.147.4.1089.
10
Expression on normal lymphocytes of two cell surface antigens, XenCSA and GIX, related to the major glycoproteins (gp70) of murine leukemia viruses.两种细胞表面抗原XenCSA和GIX在正常淋巴细胞上的表达，这两种抗原与鼠白血病病毒的主要糖蛋白（gp70）相关。
J Immunol. 1982 May;128(5):2111-5.

引用本文的文献

1
Murine leukemia virus proteins expressed on the surface of infected cells in culture.在培养的受感染细胞表面表达的鼠白血病病毒蛋白。
J Virol. 1980 Mar;33(3):936-44. doi: 10.1128/JVI.33.3.936-944.1980.
2
Structure and expression of glycoproteins controlled by the Qa-1a allele.由Qa-1a等位基因控制的糖蛋白的结构与表达
Immunogenetics. 1981 Dec;14(6):455-68. doi: 10.1007/BF00350118.
3
Malignancies of metastatic murine lymphosarcoma cell lines and clones correlate with decreased cell surface display of RNA tumor virus envelope glycoprotein gp70.转移性小鼠淋巴肉瘤细胞系和克隆的恶性肿瘤与RNA肿瘤病毒包膜糖蛋白gp70的细胞表面表达降低相关。
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5943-7. doi: 10.1073/pnas.77.10.5943.
4
Influence of Fv-1 alleles on cellular expression of gp70.Fv-1等位基因对gp70细胞表达的影响。
J Exp Med. 1980 Apr 1;151(4):980-3. doi: 10.1084/jem.151.4.980.
5
Amplified env and gag products on AKR cells. Origin from different murine leukemia virus genomes.AKR细胞上的env和gag产物扩增。源自不同的鼠白血病病毒基因组。
J Exp Med. 1980 Apr 1;151(4):975-9. doi: 10.1084/jem.151.4.975.
6
Relationships of gp70 of MuLV envelopes to gp70 components of mouse lymphocyte plasma membranes.鼠白血病病毒包膜糖蛋白70（gp70）与小鼠淋巴细胞质膜gp70成分的关系。
J Exp Med. 1978 Apr 1;147(4):1280-4. doi: 10.1084/jem.147.4.1280.
7
Isolation and comparison of murine leukemia virus-related glycoproteins from AKR and New Zealand mice.从AKR小鼠和新西兰小鼠中分离并比较鼠白血病病毒相关糖蛋白
J Virol. 1977 Apr;22(1):168-74. doi: 10.1128/JVI.22.1.168-174.1977.
8
Genetic control of resistance to tumors.对肿瘤抗性的遗传控制。
Am J Pathol. 1978 Nov;93(2):487-98.
9
Viral proteins expressed on the surface of murine leukemia cells.在鼠白血病细胞表面表达的病毒蛋白。
J Virol. 1977 Apr;22(1):65-73. doi: 10.1128/JVI.22.1.65-73.1977.

本文引用的文献

1
The G-IX system. A cell surface allo-antigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome.G-IX系统。一种与鼠白血病病毒相关的细胞表面同种异体抗原；关于病毒基因组染色体整合的意义。
J Exp Med. 1971 Jun 1;133(6):1334-55. doi: 10.1084/jem.133.6.1334.
2
Isolation and characterization of H-2 and TL alloantigens from the surface of mouse lymphocytes.从小鼠淋巴细胞表面分离并鉴定H-2和TL同种异体抗原。
Cell Immunol. 1972 Jun;4(2):187-91. doi: 10.1016/0008-8749(72)90019-6.
3
Studies on the effect of specific antisera on the metabolism of cellular antigens. I. Isolation of thymus leukemia antigens.关于特异性抗血清对细胞抗原代谢影响的研究。I. 胸腺白血病抗原的分离。
J Immunol. 1974 Apr;112(4):1285-95.
4
Leukemia-associated transplantation antigens related to murine leukemia virus. The X.1 system: immune response controlled by a locus linked to H-2.与鼠白血病病毒相关的白血病相关移植抗原。X.1系统：由与H-2连锁的基因座控制的免疫反应。
J Exp Med. 1973 Sep 1;138(3):593-606. doi: 10.1084/jem.138.3.593.
5
Diversity of envelope antigens on murine type-C RNA viruses.小鼠C型RNA病毒包膜抗原的多样性。
J Natl Cancer Inst. 1974 Apr;52(4):1189-97. doi: 10.1093/jnci/52.4.1189.
6
Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses.自然发生的鼠白血病病毒诱导的白血病抗原：它们与粗病毒及其他鼠白血病病毒抗原的关系。
J Exp Med. 1966 Oct 1;124(4):753-72. doi: 10.1084/jem.124.4.753.
7
Editorial: Murine type-C RNA viruses: a proposed reclassification, other possible pathogenicities, and a new immunologic function.
J Natl Cancer Inst. 1974 Apr;52(4):1029-34. doi: 10.1093/jnci/52.4.1029.
8
Expression of murine leukemia virus envelope glycoprotein gp69/71 on mouse thymocytes. Evidence for two structural variants distinguished by presence vs. absence of GIX antigen.小鼠白血病病毒包膜糖蛋白gp69/71在小鼠胸腺细胞上的表达。存在与不存在GIX抗原所区分的两种结构变体的证据。
J Exp Med. 1975 Aug 1;142(2):518-23. doi: 10.1084/jem.142.2.518.
9
Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. V. Identification of a new murine viral protein, p15(E).肿瘤病毒蛋白质的色谱分离与抗原分析。V. 一种新的鼠类病毒蛋白p15（E）的鉴定
J Virol. 1975 Jul;16(1):53-61. doi: 10.1128/JVI.16.1.53-61.1975.
10
Biochemical evidence linking the GIX thymocyte surface antigen to the gp69/71 envelope glycoprotein of murine leukemia virus.将GIX胸腺细胞表面抗原与鼠白血病病毒的gp69/71包膜糖蛋白联系起来的生化证据。
J Exp Med. 1975 Jan 1;141(1):198-205. doi: 10.1084/jem.141.1.198.

X-gp70：小鼠白血病病毒包膜蛋白gp70的第三种分子形式，在小鼠淋巴细胞上表达。

X-gp70: a third molecular species of the envelope protein gp70 of murine leukemia virus, expressed on mouse lymphoid cells.

作者信息

Tung J S, Shen F W, Fleissner E, Boyse E A

出版信息

J Exp Med. 1976 Apr 1;143(4):969-74. doi: 10.1084/jem.143.4.969.

DOI:10.1084/jem.143.4.969
PMID:56420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2190151/
Abstract

Three variants of the gp70 envelope component of MuLV are now recognizable serologically: GIX-gp70, 0-gp70, and X-gp70. The last of these, X-gp70, has so far been found only in mice or cells producing abundant C-type virus. This distinguishes X-gp70, provisionally, from the GIX-gp70 and 0-gp70 variants, each of which can be expressed on normal thymocytes without accompanying virus production, as exemplified by mouse strains 129 and B6, respectively. The X-gp70 genotype, however, is not limited to strains of mice-producing abundant virus, because X-gp70+ leukemias occur in strains of mice which do not produce a great deal of virus and whose thymocytes and other tissues are X-gp70-; this is analogous to the appearance of GIX+ leukemias in GIX- mouse strains.

摘要

目前，通过血清学方法可识别出莫氏白血病病毒（MuLV）包膜成分gp70的三种变体：GIX-gp70、0-gp70和X-gp70。其中，X-gp70迄今为止仅在产生大量C型病毒的小鼠或细胞中发现。这暂时将X-gp70与GIX-gp70和0-gp70变体区分开来，例如，GIX-gp70和0-gp70变体分别可在129和B6小鼠品系的正常胸腺细胞上表达，且无伴随病毒产生。然而，X-gp70基因型并不局限于产生大量病毒的小鼠品系，因为在不产生大量病毒且其胸腺细胞和其他组织为X-gp70阴性的小鼠品系中会出现X-gp70阳性白血病；这类似于GIX阴性小鼠品系中出现GIX阳性白血病的情况。