通过在高温下孵育增强人淋巴细胞在体外对植物凝血素的反应。
Enhancement of human lymphocyte responses to phytomitogens in vitro by incubation at elevated temperatures.
作者信息
Ashman R B, Nahmias A J
出版信息
Clin Exp Immunol. 1977 Sep;29(3):464-7.
Abstract
Incubation of human lymphocytes with PHA or Con A at 39 degrees C for 3 days caused a consistent, statistically significant, increase in [3H]thymidine uptake, compared with cultures incubated at 37 degrees C. The responses were also significantly increased after 2 days of incubation, suggesting that hyperthermia not only enhanced, but also caused an earlier onset of the mitogen response.
摘要
与在37摄氏度培养的细胞相比，将人淋巴细胞与PHA或Con A在39摄氏度下孵育3天会导致[3H]胸苷摄取量持续且在统计学上显著增加。孵育2天后反应也显著增强，这表明热疗不仅增强了促有丝分裂原反应，还使其更早出现。
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