关于类冠状病毒CV 777与几种冠状病毒之间抗原关系的免疫电子显微镜和免疫荧光研究。
An immunoelectron microscopic and immunofluorescent study on the antigenic relationship between the coronavirus-like agent, CV 777, and several coronaviruses.
作者信息
Pensaert M B, Debouck P, Reynolds D J
出版信息
Arch Virol. 1981;68(1):45-52. doi: 10.1007/BF01315166.
Abstract
A possible antigenic relationship between the porcine enteropathogenic coronavirus-like agent (CVLA) and 6 known coronaviruses was examined by immunoelectron microscopy (IEM) and by immunofluorescence (IF). CVLA did not show cross reactivity with infectious bronchitis virus, transmissible gastroenteritis virus (TGEV), canine coronavirus (CCV) hemagglutinating encephalomyelitis virus (HEV), neonatal calf diarrhea coronavirus (NCDCV) or feline infectious peritonitis virus (FIPV). Antigenic relationship was detected by IEM between TGEV and CCV, NCDCV and HEV and by IF between TGEV and CCV, TGEV and FIPV, HEV and NCDCV.
摘要
通过免疫电子显微镜（IEM）和免疫荧光（IF）检测了猪肠道致病性冠状病毒样病原体（CVLA）与6种已知冠状病毒之间可能存在的抗原关系。CVLA与传染性支气管炎病毒、传染性胃肠炎病毒（TGEV）、犬冠状病毒（CCV）、血凝性脑脊髓炎病毒（HEV）、新生牛腹泻冠状病毒（NCDCV）或猫传染性腹膜炎病毒（FIPV）均未表现出交叉反应。通过IEM检测到TGEV与CCV、NCDCV与HEV之间存在抗原关系，通过IF检测到TGEV与CCV、TGEV与FIPV、HEV与NCDCV之间存在抗原关系。
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