Gary G W, Black D R, Palmer E
Arch Virol. 1982;72(3):223-7. doi: 10.1007/BF01348968.
Monoclonal IgG to the inner capsid of human rotavirus was produced by mice immunized with hybrid cells derived from mouse myeloma and the spleens of mice immunized with rotavirus. This IgG reacted with an antigenic determinant of mammalian rotaviruses that was not present on that of avian rotaviruses.
用源自小鼠骨髓瘤细胞与经轮状病毒免疫的小鼠脾脏细胞融合得到的杂交细胞免疫小鼠,制备出了针对人轮状病毒内衣壳的单克隆IgG。这种IgG与哺乳动物轮状病毒的一种抗原决定簇发生反应,而该抗原决定簇不存在于禽轮状病毒的抗原决定簇中。