Mal'tseva N N, Marennikova S S, Nakano J, Matsevich G R, Khabakhpashaeva N A
Zh Mikrobiol Epidemiol Immunobiol. 1984 Apr(4):64-7.
To differentiate antibodies to monkeypox and vaccinia viruses, the solid-phase ELISA with preliminary adsorption of sera with vaccinia virus was used. The identification of antibodies in 99 serum samples obtained in the Republic of Congo from children without vaccination scars was carried out by means of this assay. No antibodies to monkeypox virus were revealed. In 62% of cases the presence of antibodies was due to vaccinia virus. In the sera of 32% of children under examination antibodies differing from those to vaccinia and monkeypox viruses were revealed. To find out the origin of these antibodies, further seroepidemiological studies are necessary.
为了区分抗猴痘病毒和痘苗病毒的抗体，采用了先用痘苗病毒对血清进行初步吸附的固相酶联免疫吸附测定法（ELISA）。通过该检测方法对在刚果共和国采集的99份无接种疤痕儿童的血清样本中的抗体进行了鉴定。未检测到抗猴痘病毒的抗体。在62%的病例中，抗体的存在是由于痘苗病毒。在32%受检儿童的血清中，检测到了与抗痘苗病毒和抗猴痘病毒不同的抗体。为了查明这些抗体的来源，有必要进一步开展血清流行病学研究。
