通过支气管镜检查期间获取的定量保护性导管培养物诊断细菌性肺部感染。
Diagnosis of bacterial pulmonary infections with quantitative protected catheter cultures obtained during bronchoscopy.
作者信息
Pollock H M, Hawkins E L, Bonner J R, Sparkman T, Bass J B
出版信息
J Clin Microbiol. 1983 Feb;17(2):255-9. doi: 10.1128/jcm.17.2.255-259.1983.
Abstract
Quantitative bacteriology was performed on specimens collected by protected catheter fiberoptic bronchoscopy from 172 patients. Of the patients who had pneumonia, 75 of 78 (96%) had one or more species present at greater than or equal to 10(3) CFU/ml, whereas 2 of 35 (6%) control patients had organisms present in that quantity. In addition, 66% of the control specimens yielded no isolates by this technique. All of the 11 patients with bronchitis had greater than or equal to 10(3) CFU/ml. Quantitative bacteriology revealed high levels of colonization in patients without infection and endobronchial structural disease. The data suggest that bacterial counts of greater than or equal to 10(3) CFU/ml in suspended secretions collected with a protected catheter brush were diagnostic of the bacteriological etiology of lower respiratory tract infections in patients without endobronchial structural abnormalities.
摘要
对通过受保护导管纤维支气管镜从172例患者采集的标本进行了定量细菌学检测。在患有肺炎的患者中，78例中有75例（96%）存在一种或多种细菌，其数量大于或等于10³CFU/ml，而35例对照患者中有2例（6%）的细菌数量达到该水平。此外，66%的对照标本通过该技术未分离出细菌。所有11例支气管炎患者的细菌数量均大于或等于10³CFU/ml。定量细菌学显示，在无感染和支气管内结构疾病的患者中存在高水平的定植。数据表明，使用受保护导管刷收集的悬浮分泌物中细菌计数大于或等于10³CFU/ml可诊断无支气管内结构异常患者下呼吸道感染的细菌学病因。
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