可的松、细胞松弛素B和放线菌酮对细胞培养中鹦鹉热衣原体菌株的影响。
Effects of cortisone, cytochalasin B and cycloheximide on strains of Chlamydia psittaci in cell cultures.
作者信息
Tessler J
出版信息
Can J Comp Med. 1983 Jul;47(3):352-7.
Abstract
Vero and McCoy cell cultures were tested for their susceptibility to Chlamydia psittaci in the presence of several antimetabolites, such as cortisone acetate, cytochalasin B and cycloheximide. Vero cells were more susceptible than the McCoy cell cultures as demonstrated by cytopathic changes, fluorescent antibody activity, and titer of C. psittaci. Although all of the antimetabolites increased these parameters, a mixture of cortisone and cytochalasin B was the most effective.
摘要
在存在几种抗代谢物（如醋酸可的松、细胞松弛素B和放线菌酮）的情况下，对Vero细胞和McCoy细胞培养物进行了鹦鹉热衣原体易感性测试。如细胞病变变化、荧光抗体活性和鹦鹉热衣原体滴度所示，Vero细胞比McCoy细胞培养物更易感染。尽管所有抗代谢物都提高了这些参数，但可的松和细胞松弛素B的混合物最为有效。
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