Francesconi R P, Sawka M N, Pandolf K B
J Appl Physiol Respir Environ Exerc Physiol. 1983 Dec;55(6):1790-4. doi: 10.1152/jappl.1983.55.6.1790.
This study was designed to assess the effects of hydration, acclimation, environment, and exercise on plasma levels of renin and aldosterone. Sixteen subjects exercised (1.34 m X s-1), both pre- and postacclimation, when euhydrated or hypohydrated (-5% of body wt) in a comfortable (20 degrees C, rh = 40%), hot-wet (35 degrees C, rh = 79%), or hot-dry (49 degrees C, rh = 20%) environment. Although light exercise in a thermoneutral environment had no effects on plasma levels of renin activity (PRA) or aldosterone (ALD), exercise in both hot environments resulted in significantly increased levels of both. Increments in both PRA and ALD were greater when hypohydrated, and PRA effects were significantly moderated by heat acclimation in both the euhydration and hypohydration experiments. Although PRA and ALD responses were generally correlated, acclimation did not consistently attenuate ALD increments. We concluded that hydration state, acclimation level, and environmental conditions all affected the responses of PRA and ALD to light exercise.
本研究旨在评估水合状态、适应性、环境和运动对肾素和醛固酮血浆水平的影响。16名受试者在适应性训练前后，于舒适环境（20℃，相对湿度=40%）、湿热环境（35℃，相对湿度=79%）或干热环境（49℃，相对湿度=20%）中，处于正常水合状态或低水合状态（体重减轻5%）时进行运动（速度为1.34米/秒）。虽然在热中性环境中进行轻度运动对肾素活性（PRA）或醛固酮（ALD）的血浆水平没有影响，但在两种热环境中运动均导致两者水平显著升高。低水合状态时，PRA和ALD的增幅更大，并且在正常水合和低水合实验中，热适应性均显著缓解了PRA的影响。虽然PRA和ALD的反应通常具有相关性，但适应性训练并未始终减弱ALD的增幅。我们得出结论，水合状态、适应水平和环境条件均会影响PRA和ALD对轻度运动的反应。
