Crapo P A, Kolterman O G
Am J Clin Nutr. 1984 Apr;39(4):525-34. doi: 10.1093/ajcn/39.4.525.
Be studied the metabolic effects of 2 wk of fructose feeding as the sweetener in the diet of 11 normal individuals. The data demonstrated 1) no adverse effects of the fructose containing diet on triglyceride, pyruvate, lactate, or uric acid metabolism; 2) no apparent adaptation in the metabolism of fructose; 3) markedly flattened postprandial serum glucose and insulin responses to pure fructose; and 4) a modest decline in postprandial glucose and insulin levels after ingestion of standard fructose containing mixed meals as compared to sucrose-containing mixed meals.
对11名正常个体的饮食中使用果糖作为甜味剂进行为期2周的喂养，研究其代谢效应。数据表明：1）含果糖饮食对甘油三酯、丙酮酸、乳酸或尿酸代谢无不良影响；2）果糖代谢无明显适应性变化；3）餐后血清葡萄糖和胰岛素对纯果糖的反应明显变平；4）与含蔗糖的混合餐相比，摄入标准含果糖混合餐后，餐后葡萄糖和胰岛素水平有适度下降。
