大鼠门腔静脉转位前后的肝血流研究。
Hepatic blood flow studies in the rat before and after portacaval transposition.
作者信息
Ryan C J, Guest J, Ryan S, Harper A M, Blumgart L H
出版信息
Br J Exp Pathol. 1978 Feb;59(1):8-12.
Portacaval transposition diverts portal blood from the liver and allows systemic venous blood from the caudal inferior vena cava to perfuse the portal bed. Measurement of hepatic tissue blood flow before and after portacaval transposition and its relationship to the liver atrophy seen after portacaval transposition is important. Sequential measurements of hepatic tissue blood flow carried out before and after portacaval transposition have been made using the clearance of the inert radioactive gas 85Krypton after injection into the portal bed. These measurements reveal that hepatic tissue blood flow is not diminished following the operation. The relative liver atrophy seen after portacaval transposition is therefore consequent on portal venous diversion but not on diminished hepatic perfusion.
门腔静脉转位将门静脉血从肝脏分流，使来自尾侧下腔静脉的体循环静脉血灌注门静脉床。测量门腔静脉转位前后的肝组织血流量及其与门腔静脉转位后出现的肝脏萎缩的关系很重要。在门腔静脉转位前后，使用惰性放射性气体氪85注入门静脉床后的清除率对肝组织血流量进行了连续测量。这些测量结果显示，术后肝组织血流量并未减少。因此，门腔静脉转位后出现的相对肝脏萎缩是由于门静脉分流，而非肝灌注减少所致。
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