男性急性淋病的两剂量阿莫西林克拉维酸钾治疗
Two dose Augmentin treatment of acute gonorrhoea in men.
作者信息
Lim K B, Rajan V S, Giam Y C, Lui E O, Sng E H, Yeo K L
出版信息
Br J Vener Dis. 1984 Jun;60(3):161-3. doi: 10.1136/sti.60.3.161.
Abstract
We studied 192 men with acute gonococcal urethritis, 97 of whom received two oral doses of Augmentin (amoxycillin 3 g and clavulanic acid 250 mg) separated by a four hour interval; the remaining 95 received 2 g kanamycin in a single intramuscular injection. Of the patients treated with Augmentin, 93 (95.9%) were cured, which was significantly more than the 83 (87.4%) patients treated with kanamycin. Augmentin was equally effective in the treatment of penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG infections, the cure rates for which were 96.6% and 95.6% respectively.
摘要
我们研究了192例急性淋菌性尿道炎男性患者，其中97例接受两次口服奥格门汀（阿莫西林3g和克拉维酸250mg），间隔4小时；其余95例接受单次肌内注射2g卡那霉素。接受奥格门汀治疗的患者中，93例（95.9%）治愈，这显著高于接受卡那霉素治疗的83例（87.4%）患者。奥格门汀在治疗产青霉素酶淋病奈瑟菌（PPNG）和非PPNG感染方面同样有效，其治愈率分别为96.6%和95.6%。
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引用本文的文献
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2
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3
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本文引用的文献
1
Simple method for detecting penicillinase-producing Neisseria gonorrhoeae and Staphylococcus aureus.检测产青霉素酶淋病奈瑟菌和金黄色葡萄球菌的简易方法。
Br J Vener Dis. 1981 Apr;57(2):141-2. doi: 10.1136/sti.57.2.141.
2
Susceptibility of Neisseria gonorrhoeae to cefotaxime and ceftizoxime.淋病奈瑟菌对头孢噻肟和头孢唑肟的敏感性。
Br J Vener Dis. 1981 Jun;57(3):162-4. doi: 10.1136/sti.57.3.162.
3
HR 756--a new cephalosporin in the treatment of gonorrhoea caused by ordinary and penicillinase-producing strains of Neisseria gonorrhoeae.HR 756——一种用于治疗由普通淋病奈瑟菌菌株和产青霉素酶淋病奈瑟菌菌株引起的淋病的新型头孢菌素。
Br J Vener Dis. 1980 Aug;56(4):255-8. doi: 10.1136/sti.56.4.255.
4
Spectinomycin dihydrochloride treatment of gonorrhoea.盐酸大观霉素治疗淋病。
Singapore Med J. 1972 Jun;13(3):161-2.
5
Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus.克拉维酸：一种来自棒状链霉菌的β-内酰胺酶抑制性β-内酰胺类抗生素。
Antimicrob Agents Chemother. 1977 May;11(5):852-7. doi: 10.1128/AAC.11.5.852.
6
Epidemiology and treatment of penicillinase-producing Neisseria gonorrhoeae.产青霉素酶淋病奈瑟菌的流行病学与治疗
Sex Transm Dis. 1979 Apr-Jun;6(2 Suppl):152-8. doi: 10.1097/00007435-197904000-00021.
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Antibiotic susceptibility of Neisseria gonorrhoeae strains from Europe and Africa.来自欧洲和非洲的淋病奈瑟菌菌株的抗生素敏感性
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Inhibition of beta-lactamase in Neisseria gonorrhoeae by sodium clavulanate.棒酸对淋病奈瑟菌中β-内酰胺酶的抑制作用。
Antimicrob Agents Chemother. 1978 Nov;14(5):794-6. doi: 10.1128/AAC.14.5.794.
9
Penicillinase-producing Neisseria gonorrhoeae.产青霉素酶淋病奈瑟菌
Lancet. 1976 Sep 25;2(7987):657-8. doi: 10.1016/s0140-6736(76)92467-3.
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Beta-lactamase-producing, penicillin-resistant gonococcus.产β-内酰胺酶、耐青霉素的淋球菌。
Lancet. 1976 Sep 25;2(7987):656-7. doi: 10.1016/s0140-6736(76)92466-1.
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