Hedgpeth J, Clement J M, Marchal C, Perrin D, Hofnung M
Proc Natl Acad Sci U S A. 1980 May;77(5):2621-5. doi: 10.1073/pnas.77.5.2621.
lamB encodes the lambda receptor of Escherichia coli, an outer membrane protein. We have identified the beginning of the lamB gene by correlating DNA nucleotide sequence with a partial sequence of the primary translation product of lamB. We show that lambda receptor is synthesized as a precursor containing an extra 25 amino acids at its NH2 terminus. These amino acids are predominately hydrophobic and probably comprise a structure required for initiation of transport of lambda receptor from the cytoplasm to the outer membrane.
lamB编码大肠杆菌的λ受体,一种外膜蛋白。我们通过将DNA核苷酸序列与lamB初级翻译产物的部分序列相关联,确定了lamB基因的起始位置。我们发现λ受体是以一种在其NH2末端含有额外25个氨基酸的前体形式合成的。这些氨基酸主要是疏水的,可能构成了λ受体从细胞质转运到外膜起始过程所需的一种结构。