Alanko A, Heinonen E, Scheinin T M, Tolppanen E M, Vihko R
Br J Cancer. 1984 Nov;50(5):667-72. doi: 10.1038/bjc.1984.234.
Oestrogen and progesterone receptor assays were performed in 286 women with primary breast cancer, and the patient group was followed up for a minimum of 24 months. Of the 263 patients belonging to clinical stages I-III and serving as the population used for calculation of disease-free interval only 1.9% received postoperative endocrine treatment and 6.5% chemotherapy. No significant relationship between the presence or concentrations of oestrogen or progesterone receptor and the disease-free interval was observed. It is therefore possible that the positive relationship between these variables reported in some investigations reflects an influence by adjuvant endocrine measures.
对286例原发性乳腺癌女性患者进行了雌激素和孕激素受体检测，并对患者组进行了至少24个月的随访。在属于临床I - III期且用作无病生存期计算人群的263例患者中，仅1.9%接受了术后内分泌治疗，6.5%接受了化疗。未观察到雌激素或孕激素受体的存在或浓度与无病生存期之间存在显著关系。因此，一些研究报告的这些变量之间的正相关关系可能反映了辅助内分泌措施的影响。
