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DNA序列分析：一种在众多序列中寻找同源性的程序。

DNA sequence analysis: a procedure to find homologies among many sequences.

作者信息

Krishnan G, Kaul R K, Jagadeeswaran P

出版信息

Nucleic Acids Res. 1986 Jan 10;14(1):543-50. doi: 10.1093/nar/14.1.543.

DOI:10.1093/nar/14.1.543
PMID:3753788
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339439/
Abstract

SEQCMP, a program that analyzes and searches for homology among multiple nucleic acid sequences, is described. The sequences are compared by the dot matrix method and the consensus sequence is derived by superimposing all the dot matrices on one another. The program is written in MBASIC and runs on IBM-PC microcomputer. It is interactive and can be used by investigators with no computer background or experience.

摘要

介绍了SEQCMP程序，它可分析多个核酸序列并搜索它们之间的同源性。通过点阵法对序列进行比较，并将所有点阵相互叠加得出共有序列。该程序用MBASIC编写，在IBM-PC微型计算机上运行。它具有交互性，没有计算机背景或经验的研究人员也可以使用。

相似文献

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引用本文的文献

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A multiple sequence comparison method.一种多序列比对方法。
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本文引用的文献

1
A computer program to search for tRNA genes.一个用于搜索转运RNA基因的计算机程序。
Nucleic Acids Res. 1980 Feb 25;8(4):817-25.
2
Enhanced graphic matrix analysis of nucleic acid and protein sequences.核酸和蛋白质序列的增强图形矩阵分析
Proc Natl Acad Sci U S A. 1981 Dec;78(12):7665-9. doi: 10.1073/pnas.78.12.7665.
3
Matrix program to analyze primary structure homology.用于分析一级结构同源性的矩阵程序。
Nucleic Acids Res. 1982 Jan 11;10(1):127-31. doi: 10.1093/nar/10.1.127.
4
Use of statistical criteria for screening potential homologies in nucleic acid sequences.使用统计标准筛选核酸序列中的潜在同源性。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):203-13. doi: 10.1093/nar/12.1part1.203.
5
Microcomputer programs for graphic analysis of nucleic acid and protein sequences.用于核酸和蛋白质序列图形分析的微机程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):811-7. doi: 10.1093/nar/12.1part2.811.
6
Simplified computer programs for search of homology within nucleotide sequences.用于搜索核苷酸序列同源性的简化计算机程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):193-201. doi: 10.1093/nar/12.1part1.193.
7
The gene structure of human anti-haemophilic factor IX.人抗血友病因子IX的基因结构
EMBO J. 1984 May;3(5):1053-60. doi: 10.1002/j.1460-2075.1984.tb01926.x.
8
A DNA analysis program designed for computer novices working in an industrial-research environment.一款为在工业研究环境中工作的计算机新手设计的DNA分析程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):367-78. doi: 10.1093/nar/12.1part1.367.
9
Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin.人凝血酶原互补脱氧核糖核酸及编码基因的特性分析
Biochemistry. 1983 Apr 26;22(9):2087-97. doi: 10.1021/bi00278a008.
10
Interactive computer programs in sequence data analysis.序列数据分析中的交互式计算机程序。
Nucleic Acids Res. 1982 Jan 11;10(1):433-47. doi: 10.1093/nar/10.1.433.