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DNA序列分析:一种在众多序列中寻找同源性的程序。

DNA sequence analysis: a procedure to find homologies among many sequences.

作者信息

Krishnan G, Kaul R K, Jagadeeswaran P

出版信息

Nucleic Acids Res. 1986 Jan 10;14(1):543-50. doi: 10.1093/nar/14.1.543.

Abstract

SEQCMP, a program that analyzes and searches for homology among multiple nucleic acid sequences, is described. The sequences are compared by the dot matrix method and the consensus sequence is derived by superimposing all the dot matrices on one another. The program is written in MBASIC and runs on IBM-PC microcomputer. It is interactive and can be used by investigators with no computer background or experience.

摘要

介绍了SEQCMP程序,它可分析多个核酸序列并搜索它们之间的同源性。通过点阵法对序列进行比较,并将所有点阵相互叠加得出共有序列。该程序用MBASIC编写,在IBM-PC微型计算机上运行。它具有交互性,没有计算机背景或经验的研究人员也可以使用。

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