Wilders M M, Drexhage H A, Weltevreden E F, Mullink H, Duijvestijn A, Meuwissen S G
Immunology. 1983 Mar;48(3):453-60.
The antigen presenting cell system in the skin is extensively studied, and is supposed to consist of Langerhans cells in epidermis and dermis, veiled cells in skin lymph and interdigitating cells in skin lymph nodes. In order to detect whether a similar cell system is present in the gut, we studied Peyer's patch cell suspensions. Mononuclear cells with long actively moving cytoplasmic veils were found in cell suspensions from Peyer's patches of rat, guinea-pig, and pig, and in cell suspensions from small intestinal villi of guinea-pig and pig, but not of rat. These veiled cells are strongly Ia-positive. Because of their Ia positivity, their enzyme cytochemical staining pattern, and their ultrastructure, these cells resemble the antigen presenting cells of the skin, skin lymph and lymph node.
皮肤中的抗原呈递细胞系统已得到广泛研究，一般认为它由表皮和真皮中的朗格汉斯细胞、皮肤淋巴液中的面纱细胞以及皮肤淋巴结中的交错突细胞组成。为了检测肠道中是否存在类似的细胞系统，我们研究了派尔集合淋巴结细胞悬液。在大鼠、豚鼠和猪的派尔集合淋巴结细胞悬液以及豚鼠和猪的小肠绒毛细胞悬液中发现了具有长而活跃移动的胞质面纱的单核细胞，但在大鼠的上述悬液中未发现。这些面纱细胞Ia强阳性。由于其Ia阳性、酶细胞化学染色模式以及超微结构，这些细胞类似于皮肤、皮肤淋巴液和淋巴结中的抗原呈递细胞。
