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派尔集合淋巴结中的大单核Ia阳性被膜细胞。II. 在大鼠派尔集合淋巴结中的定位

Large mononuclear Ia-positive veiled cells in Peyer's patches. II. Localization in rat Peyer's patches.

作者信息

Wilders M M, Sminia T, Plesch B E, Drexhage H A, Weltevreden E F, Meuwissen S G

出版信息

Immunology. 1983 Mar;48(3):461-7.

PMID:6337945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1454035/
Abstract

Dendritic Ia-positive veiled cells were seen in frozen sections of rat Peyer's patches within the lymphoepithelium, in the reticular area just underneath and in the T-dependent interfollicular area. From immunohistochemical stainings with anti-IgA, IgE, IgG, IgM and monoclonal anti T lymphocyte sera it is concluded that these Ia-positive cells do not belong to lymphocyte series. The ultrastructure of these Ia-positive veiled cells resembled the morphology of the veiled cells found in Peyer's patch cell suspensions and in skin lymph. It is suggested that these cells form an antigen presenting cell system in mucosa-associated lymphoid tissue, similar to the antigen presenting cell system in the skin.

摘要

在大鼠派尔集合淋巴结的冰冻切片中,可见树突状Ia阳性的被膜细胞位于淋巴上皮内、其下方的网状区域以及T细胞依赖的滤泡间区域。通过抗IgA、IgE、IgG、IgM和单克隆抗T淋巴细胞血清的免疫组织化学染色得出结论,这些Ia阳性细胞不属于淋巴细胞系列。这些Ia阳性被膜细胞的超微结构类似于在派尔集合淋巴结细胞悬液和皮肤淋巴中发现的被膜细胞的形态。提示这些细胞在黏膜相关淋巴组织中形成了一个抗原呈递细胞系统,类似于皮肤中的抗原呈递细胞系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/f7c79e3fea43/immunology00220-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/47af7cb89842/immunology00220-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/765405443a37/immunology00220-0050-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/c382d092aa6d/immunology00220-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/42a55560e9c0/immunology00220-0051-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/f7c79e3fea43/immunology00220-0052-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/47af7cb89842/immunology00220-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/765405443a37/immunology00220-0050-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/c382d092aa6d/immunology00220-0051-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/42a55560e9c0/immunology00220-0051-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f8e/1454035/f7c79e3fea43/immunology00220-0052-a.jpg

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本文引用的文献

1
Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.通过添加供体品系树突状细胞恢复去除过客细胞的肾移植异体移植物的免疫原性。
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Large mononuclear Ia-positive veiled cells in Peyer's patches. I. Isolation and characterization in rat, guinea-pig and pig.派伊尔结中的大型单核Ia阳性被膜细胞。I. 大鼠、豚鼠和猪的分离与特性研究
Immunology. 1983 Mar;48(3):453-60.
3
Dendritic cells: features and functions.树突状细胞:特征与功能
大鼠大肠抗原采样结构的形态学研究
Infect Immun. 1984 Feb;43(2):693-9. doi: 10.1128/iai.43.2.693-699.1984.
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Veiled cells in chronic idiopathic inflammatory bowel disease.慢性特发性炎症性肠病中的隐蔽细胞
Clin Exp Immunol. 1984 Feb;55(2):377-87.
5
Ontogeny of non-lymphoid and lymphoid cells in the rat gut with special reference to large mononuclear Ia-positive dendritic cells.大鼠肠道中非淋巴细胞和淋巴细胞的个体发生,特别提及大单核Ia阳性树突状细胞。
Immunology. 1983 Oct;50(2):303-14.
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Peripolesis followed by cytotoxicity in chronic idiopathic inflammatory bowel disease.慢性特发性炎症性肠病中噬围现象继以细胞毒性作用。
Clin Exp Immunol. 1984 Sep;57(3):614-20.
7
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J Clin Invest. 1984 Jul;74(1):90-5. doi: 10.1172/JCI111423.
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Functional characteristics of the veiled cells in afferent lymph from the rat intestine.大鼠肠道传入淋巴中隐蔽细胞的功能特性
Immunology. 1986 Jul;58(3):379-87.
9
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Vet Res Commun. 1988;12(1):47-59. doi: 10.1007/BF00396403.
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An immunohistochemical study of cells with surface and cytoplasmic immunoglobulins in situ in Peyer's patches and lamina propria of rat small intestine.大鼠小肠派尔集合淋巴结和固有层中表面及胞质免疫球蛋白原位细胞的免疫组织化学研究。
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The light and the electron microscopic studies of Peyer's patches in non germ-free adult mice.非无菌成年小鼠派尔集合淋巴结的光镜和电镜研究。
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