Dahlberg-Lagergård T
J Clin Microbiol. 1983 Mar;17(3):428-31. doi: 10.1128/jcm.17.3.428-431.1983.
Bactericidal antibodies against components of Haemophilus influenzae other than the capsular polysaccharide were analyzed in sera from patients infected with this organism and compared with the antibody levels in sera from a normal population. Such antibodies could be demonstrated in sera from about one-third of patients infected with H. influenzae type b, including children less than 1 year old. It is possible that these antibodies were directed against outer membrane proteins, since they persisted after absorption with capsular polysaccharide type b and lipopolysaccharide. These findings suggest a protective role for antibodies directed against outer membrane components, possibly proteins, in infections caused by capsulated strains of H. influenzae.
对感染流感嗜血杆菌的患者血清中针对除荚膜多糖外的流感嗜血杆菌成分的杀菌抗体进行了分析，并与正常人群血清中的抗体水平进行了比较。在约三分之一感染b型流感嗜血杆菌的患者血清中可检测到此类抗体，包括1岁以下儿童。这些抗体可能是针对外膜蛋白的，因为它们在用b型荚膜多糖和脂多糖吸收后仍持续存在。这些发现表明，针对外膜成分（可能是蛋白质）的抗体在由包膜型流感嗜血杆菌引起的感染中具有保护作用。
