空气污染物与癌症转移的促进作用。
Air pollutants and the facilitation of cancer metastasis.
作者信息
Richters A, Kuraitis K
出版信息
Environ Health Perspect. 1983 Oct;52:165-8. doi: 10.1289/ehp.8352165.
Abstract
Studies have been carried out to determine whether the inhalation of ambient levels of nitrogen dioxide (NO2), a common air pollutant, could influence the frequency of blood-borne cancer cell metastasis to the lungs. B16 mouse melanoma cells were used as an in vivo test model. the results have indicated that animals inhaling ambient levels of NO2 developed a significantly higher number of melanoma nodules in their lungs than the animals inhaling filtered air. Thus, a new concept for the action of air pollutants is proposed. The question is raised whether similar events are taking place in urban human populations.
摘要
已经开展了多项研究，以确定吸入环境水平的二氧化氮（NO2，一种常见的空气污染物）是否会影响血源性癌细胞转移至肺部的频率。B16小鼠黑色素瘤细胞被用作体内测试模型。结果表明，吸入环境水平NO2的动物肺部出现的黑色素瘤结节数量明显高于吸入过滤空气的动物。因此，提出了一个关于空气污染物作用的新概念。人们提出疑问，类似的情况是否正在城市人群中发生。
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