Nilsson B Y
J Neurol Neurosurg Psychiatry. 1978 Jun;41(6):499-504. doi: 10.1136/jnnp.41.6.499.
Visual evoked responses have been elicited by reversal of a black and white checkerboard pattern and also by a display of light-emitting diodes (LED) generating a reversal of a pattern of illuminated red circular areas. In a control group the LED display produced responses of lower amplitude and shorter latency compared to responses to checkerboard stimulation. In patients with a definite or probable diagnosis of multiple sclerosis the stimulators were equally effective in evoking pathological responses; in patients with a possible but less certain diagnosis abnormal responses were found in a higher percentage when the LED stimulus was used. Differences in stimulus field size and in stimulus colour are discussed as possible reasons for this result.
视觉诱发电位可通过黑白棋盘格图案的反转来诱发，也可通过发光二极管（LED）显示产生红色圆形照明区域图案的反转来诱发。在一个对照组中，与棋盘格刺激所产生的反应相比，LED显示产生的反应幅度较低且潜伏期较短。在明确诊断或可能诊断为多发性硬化症的患者中，两种刺激方式在诱发病理反应方面同样有效；在可能但不太确定诊断的患者中，使用LED刺激时发现异常反应的百分比更高。文中讨论了刺激场大小和刺激颜色的差异作为这一结果的可能原因。
