Moshakis V, McIlhinney R, Raghavan D, Neville A M
J Clin Pathol. 1981 Mar;34(3):314-9. doi: 10.1136/jcp.34.3.314.
The use of monoclonal antibodies which can be raised to antigens of choice offers a selective and specific approach for the detection of tumours both in vivo and at a cellular level in biopsy specimens. We demonstrate that a monoclonal antibody raised to human teratoma will localise in a teratoma, growing as a xenograft in immune-suppressed mice.
能够针对选定抗原产生的单克隆抗体,为在体内和活检标本的细胞水平上检测肿瘤提供了一种选择性和特异性的方法。我们证明,一种针对人畸胎瘤产生的单克隆抗体将定位在作为异种移植瘤生长于免疫抑制小鼠体内的畸胎瘤中。