免疫球蛋白同种异型与对B群脑膜炎球菌多糖的免疫反应
Immunoglobulin allotypes and immune response to meningococcal group B polysaccharide.
作者信息
Pandey J P, Zollinger W D, Fudenberg H H, Loadholt C B
出版信息
J Clin Invest. 1981 Nov;68(5):1378-80. doi: 10.1172/jci110387.
Abstract
Serum samples were collected from 120 healthy adult volunteers (105 Caucasians and 15 Negros) before and after immunization with meningococcal polysaccharide (MPS) group B vaccine. Antibodies to MPS group B were measured and sera were typed for several Gm and Km(1) allotypes. A significant association was found between the Km(1) allotype and immune response to MPS group B in Caucasians.
摘要
在120名健康成年志愿者（105名白种人和15名黑人）接种B群脑膜炎球菌多糖（MPS）疫苗之前和之后采集血清样本。检测针对B群MPS的抗体，并对血清进行几种Gm和Km(1)同种异型分型。在白种人中发现Km(1)同种异型与对B群MPS的免疫反应之间存在显著关联。
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