• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Structure of the 5'-terminal untranslated region of the genomic RNAs from two strains of alfalfa mosaic virus.

作者信息

Ravelonandro M, Godefroy-Colburn T, Pinck L

出版信息

Nucleic Acids Res. 1983 May 11;11(9):2815-26. doi: 10.1093/nar/11.9.2815.

DOI:10.1093/nar/11.9.2815
PMID:6856476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC325925/
Abstract

We report the sequences of the 5'-terminal regions of the 3 Alfalfa Mosaic Virus genomic RNAs for the Strasbourg strain (AlMV-S) and for a new isolate, AlMV-B; they are compared to similar data obtained by Koper-Zwarthoff et al. (Nucleic Acids Res. 1980, 8, 5635-5647) for strain 425. The structure of these leaders is highly conserved in RNAs 1 and 2. The length of the leader is 102, 100 and 101 nucleotides in RNA1 for strains S, B and 425 respectively; 55 and 56 in RNA2 for strains S and B respectively. In RNA3 however, there are important differences near the 5'-terminus between strain S and the other two: The total leader length is 258 nucleotides for strain S and 242 for strain B. The secondary structure models show a conserved hairpin near the 5'-end of each genomic RNA of AlMV-S. This hairpin is inexistent in RNA3 of the B and 425 strains. The degree of base-pairing increases with leader length. The initiator codon is located in a single stranded region in RNA2 whereas it is found in a hairpin stem in RNA 3.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db73/325925/95926627f42c/nar00354-0318-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db73/325925/95926627f42c/nar00354-0318-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db73/325925/95926627f42c/nar00354-0318-a.jpg

相似文献

1
Structure of the 5'-terminal untranslated region of the genomic RNAs from two strains of alfalfa mosaic virus.
Nucleic Acids Res. 1983 May 11;11(9):2815-26. doi: 10.1093/nar/11.9.2815.
2
Competitive multiplication of RNA3 species of different strains of alfalfa mosaic virus.不同株系苜蓿花叶病毒RNA3种类的竞争性增殖
J Gen Virol. 1989 Mar;70 ( Pt 3):777-82. doi: 10.1099/0022-1317-70-3-777.
3
Nucleotide sequence of the 3'-noncoding region of alfalfa mosaic virus RNA 4 and its homology with the genomic RNAs.苜蓿花叶病毒RNA 4 3'-非编码区的核苷酸序列及其与基因组RNA的同源性。
Nucleic Acids Res. 1979 Dec 11;7(7):1887-900. doi: 10.1093/nar/7.7.1887.
4
Complete nucleotide sequence of alfalfa mosaic virus RNA 2.苜蓿花叶病毒RNA 2的完整核苷酸序列。
Nucleic Acids Res. 1983 May 25;11(10):3019-25. doi: 10.1093/nar/11.10.3019.
5
Complete nucleotide sequence of alfalfa mosaic virus RNA 1.苜蓿花叶病毒RNA 1的完整核苷酸序列。
Nucleic Acids Res. 1983 Mar 11;11(5):1253-65. doi: 10.1093/nar/11.5.1253.
6
Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus RNAs and the intercistronic junction in RNA 3.苜蓿花叶病毒RNA 5'末端的核苷酸序列以及RNA 3中的顺反子间连接区。
Nucleic Acids Res. 1980 Dec 11;8(23):5635-47. doi: 10.1093/nar/8.23.5635.
7
Role of the 5' leader sequence of alfalfa mosaic virus RNA 3 in replication and translation of the viral RNA.苜蓿花叶病毒RNA 3的5'前导序列在病毒RNA复制和翻译中的作用
Nucleic Acids Res. 1993 Mar 25;21(6):1361-7. doi: 10.1093/nar/21.6.1361.
8
Complete nucleotide sequence of alfalfa mosaic virus RNA3.苜蓿花叶病毒RNA3的完整核苷酸序列
Nucleic Acids Res. 1983 May 11;11(9):2881-91. doi: 10.1093/nar/11.9.2881.
9
Complete nucleotide sequence of RNA 3 from alfalfa mosaic virus, strain S.苜蓿花叶病毒S株RNA 3的完整核苷酸序列
Biochimie. 1984 May;66(5):395-402. doi: 10.1016/0300-9084(84)90023-3.
10
Nucleotide sequence of 5' terminus of alfalfa mosaic virus RNA 4 leading into coat protein cistron.苜蓿花叶病毒RNA 4 5'末端进入外壳蛋白顺反子的核苷酸序列。
Proc Natl Acad Sci U S A. 1977 Dec;74(12):5504-8. doi: 10.1073/pnas.74.12.5504.

引用本文的文献

1
Subgenomic RNAs with nucleotide sequences derived from RNAs 1 and 2 of cucumber mosaic virus can act as messenger RNAs in vitro.具有源自黄瓜花叶病毒RNA 1和RNA 2的核苷酸序列的亚基因组RNA在体外可充当信使RNA。
Virology. 1985 Apr 15;142(1):144-57. doi: 10.1016/0042-6822(85)90429-5.
2
The 5' untranslated region of alfalfa mosaic virus RNA 1 is involved in negative-strand RNA synthesis.苜蓿花叶病毒RNA 1的5'非翻译区参与负链RNA的合成。
J Virol. 2003 Oct;77(20):11284-9. doi: 10.1128/jvi.77.20.11284-11289.2003.
3
Mutations in coat protein binding sites of alfalfa mosaic virus RNA 3 affect subgenomic RNA 4 accumulation and encapsidation of viral RNAs.

本文引用的文献

1
Nucleotide sequence at the 5' extremity of turnip yellow mosaic virus genome RNA.芜菁黄花叶病毒基因组RNA 5'末端的核苷酸序列。
Proc Natl Acad Sci U S A. 1978 Jul;75(7):3168-72. doi: 10.1073/pnas.75.7.3168.
2
Complete nucleotide sequence of alfalfa mosaic virus RNA 4.苜蓿花叶病毒RNA 4的完整核苷酸序列
Nucleic Acids Res. 1980 May 24;8(10):2213-23. doi: 10.1093/nar/8.10.2213.
3
Protection of satellite tobacco necrosis virus ribonucleic acid by wheat germ 40S and 80S ribosomes.小麦胚芽40S和80S核糖体对卫星烟草坏死病毒核糖核酸的保护作用。
苜蓿花叶病毒RNA 3外壳蛋白结合位点的突变影响亚基因组RNA 4的积累及病毒RNA的包装。
J Virol. 1997 Nov;71(11):8385-91. doi: 10.1128/JVI.71.11.8385-8391.1997.
4
Identification of a ribosome-binding site for a leader peptide encoded by Rous sarcoma virus RNA.劳氏肉瘤病毒RNA编码的前导肽核糖体结合位点的鉴定。
J Virol. 1984 Sep;51(3):722-9. doi: 10.1128/JVI.51.3.722-729.1984.
Biochemistry. 1980 May 13;19(10):2276-83. doi: 10.1021/bi00551a044.
4
Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes.侧翼核苷酸在真核生物核糖体识别AUG起始密码子中的可能作用。
Nucleic Acids Res. 1981 Oct 24;9(20):5233-52. doi: 10.1093/nar/9.20.5233.
5
Binding of ribosomes to the 5' leader sequence (N = 258) of RNA 3 from alfalfa mosaic virus.核糖体与苜蓿花叶病毒RNA 3的5'前导序列（N = 258）的结合。
Nucleic Acids Res. 1981 Mar 11;9(5):1087-100. doi: 10.1093/nar/9.5.1087.
6
A possible novel interaction between the 3'-end of 18 S ribosomal RNA and the 5'-leader sequence of many eukaryotic messenger RNAs.18 S核糖体RNA的3'端与许多真核生物信使RNA的5'前导序列之间可能存在一种新型相互作用。
FEBS Lett. 1982 Oct 18;147(2):133-6. doi: 10.1016/0014-5793(82)81026-0.
7
The secondary structure of the protein L1 binding region of ribosomal 23S RNA. Homologies with putative secondary structures of the L11 mRNA and of a region of mitochondrial 16S rRNA.核糖体23S RNA的蛋白质L1结合区域的二级结构。与L11 mRNA的假定二级结构以及线粒体16S rRNA一个区域的同源性。
Nucleic Acids Res. 1981 Jan 24;9(2):293-307. doi: 10.1093/nar/9.2.293.
8
Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus RNAs and the intercistronic junction in RNA 3.苜蓿花叶病毒RNA 5'末端的核苷酸序列以及RNA 3中的顺反子间连接区。
Nucleic Acids Res. 1980 Dec 11;8(23):5635-47. doi: 10.1093/nar/8.23.5635.
9
The location of the first AUG codons in cowpea mosaic virus RNAs.豇豆花叶病毒RNA中首个AUG密码子的位置。
Nucleic Acids Res. 1982 Aug 25;10(16):4861-72. doi: 10.1093/nar/10.16.4861.
10
Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information.利用热力学和辅助信息对大型RNA序列进行最优计算机折叠
Nucleic Acids Res. 1981 Jan 10;9(1):133-48. doi: 10.1093/nar/9.1.133.