Hambleton P, Broster M G, Dennis P J, Henstridge R, Fitzgeorge R, Conlan J W
J Hyg (Lond). 1983 Jun;90(3):451-60. doi: 10.1017/s0022172400029090.
Aqueous suspensions of virulent Legionella pneumophila grown on solid medium retained virulence and aerosol survival characteristics for several months. Significant numbers of viable organisms were recovered from aerosols held at various relative humidities (r.h.) for up to 2 h. The organisms survived best at 65% r.h. and were least stable at 55% r.h. Exponential phase broth-grown organisms survived poorly in aerosols in comparison with stationary phase broth cultures or organisms grown on solid medium, suggesting that the metabolic status of Legionella pneumophila organisms may be an important factor affecting their ability to survive in aerosols and cause respiratory disease.
在固体培养基上生长的强毒嗜肺军团菌的水悬液可保持毒力和气溶胶存活特性数月之久。在不同相对湿度(r.h.)下保持长达2小时的气溶胶中可回收大量活的微生物。这些微生物在相对湿度65%时存活最佳,在相对湿度55%时最不稳定。与稳定期肉汤培养物或在固体培养基上生长的微生物相比,指数生长期肉汤培养的微生物在气溶胶中的存活能力较差,这表明嗜肺军团菌微生物的代谢状态可能是影响其在气溶胶中存活及引发呼吸道疾病能力的一个重要因素。