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强毒嗜肺军团菌在气溶胶中的存活情况。

Survival of virulent Legionella pneumophila in aerosols.

作者信息

Hambleton P, Broster M G, Dennis P J, Henstridge R, Fitzgeorge R, Conlan J W

出版信息

J Hyg (Lond). 1983 Jun;90(3):451-60. doi: 10.1017/s0022172400029090.

DOI:10.1017/s0022172400029090
PMID:6863914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2134264/
Abstract

Aqueous suspensions of virulent Legionella pneumophila grown on solid medium retained virulence and aerosol survival characteristics for several months. Significant numbers of viable organisms were recovered from aerosols held at various relative humidities (r.h.) for up to 2 h. The organisms survived best at 65% r.h. and were least stable at 55% r.h. Exponential phase broth-grown organisms survived poorly in aerosols in comparison with stationary phase broth cultures or organisms grown on solid medium, suggesting that the metabolic status of Legionella pneumophila organisms may be an important factor affecting their ability to survive in aerosols and cause respiratory disease.

摘要

在固体培养基上生长的强毒嗜肺军团菌的水悬液可保持毒力和气溶胶存活特性数月之久。在不同相对湿度(r.h.)下保持长达2小时的气溶胶中可回收大量活的微生物。这些微生物在相对湿度65%时存活最佳,在相对湿度55%时最不稳定。与稳定期肉汤培养物或在固体培养基上生长的微生物相比,指数生长期肉汤培养的微生物在气溶胶中的存活能力较差,这表明嗜肺军团菌微生物的代谢状态可能是影响其在气溶胶中存活及引发呼吸道疾病能力的一个重要因素。

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本文引用的文献

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Effect of Water Vapor on Lyophilized Serratia marcescens and Escherichia coli.水蒸气对冻干粘质沙雷氏菌和大肠杆菌的影响。
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The efficiency of various liquid impinger samplers in bacterial aerosols.各种液体冲击式采样器在细菌气溶胶中的效率。
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Legionnaires' disease outbreak at an Atlanta, Georgia, Country Club: evidence for spread from an evaporative condenser.佐治亚州亚特兰大一家乡村俱乐部发生军团病疫情:源自蒸发式冷凝器的传播证据。
Am J Epidemiol. 1980 Apr;111(4):425-31. doi: 10.1093/oxfordjournals.aje.a112917.
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Survival of Legionella pneumophila in aerosols: effect of relative humidity.嗜肺军团菌在气溶胶中的存活:相对湿度的影响。
J Infect Dis. 1980 May;141(5):689. doi: 10.1093/infdis/141.5.689.
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J Infect Dis. 1980 Feb;141(2):186-92. doi: 10.1093/infdis/141.2.186.
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An outbreak of Legionnaires' disease associated with a contaminated air-conditioning cooling tower.一起与受污染的空调冷却塔相关的军团病暴发。
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Epidemic Legionnaires' disease. Airborne transmission down a chimney.
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