Glober G A, Kamiyama S, Nomura A, Shimada A, Abba B C
Lancet. 1977 Jul 16;2(8029):110-1. doi: 10.1016/s0140-6736(77)90120-9.
It has been suggested that the risk of cancer, polyposis, and diverticulosis of the large bowel increases with bowel transit-time. Hence, Japanese inhabitants of Hawaii, in whom the risk of these diseases is high, would be expected to have longer transit-times than Japanese in Japan, in whom such risks are low. However, bowel transit-times were similar in Japanese groups. Stools from the Hawaii Japanese did weight significantly less than the specimens from Japan, and this factor may be indirectly related to the risk of colorectal cancer, polyposis, or diverticulosis in the Japanese.
有人提出,患大肠癌、息肉病和憩室病的风险会随着肠道运输时间的增加而上升。因此,预计这些疾病风险较高的夏威夷日裔居民的肠道运输时间会比风险较低的日本本土日裔居民更长。然而,两个日裔群体的肠道运输时间相似。夏威夷日裔的粪便重量明显低于日本本土日裔的样本,这一因素可能与日裔患结直肠癌、息肉病或憩室病的风险存在间接关联。