从灌注的牛肉肾上腺中释放脑啡肽和含脑啡肽的多肽。
Release of enkephalins and enkephalin-containing polypeptides from perfused beef adrenal glands.
作者信息
Kilpatrick D L, Lewis R V, Stein S, Udenfriend S
出版信息
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7473-5. doi: 10.1073/pnas.77.12.7473.
Abstract
Enkephalins and enkephalin-containing polypeptides were released from perfused bovine adrenal glands by nicotine and Ba2+, agents that release catecholamines. All the enkephalin-containing polypeptides that are normally found in the adrenal medulla were released by the two secretagogues in approximately the same proportions as are present in adrenal chromaffin granules.
摘要
脑啡肽和含脑啡肽的多肽可由尼古丁和Ba2+从灌注的牛肾上腺中释放出来，尼古丁和Ba2+是能释放儿茶酚胺的物质。肾上腺髓质中正常存在的所有含脑啡肽的多肽，均可被这两种促分泌素以与肾上腺嗜铬颗粒中大致相同的比例释放出来。
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本文引用的文献
1
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J Pharmacol Exp Ther. 1962 Dec;138:360-75.
2
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Adv Biochem Psychopharmacol. 1980;22:167-79.
3
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