Fish D C, Demarais J T, Djurickovic D B, Huebner R J
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2526-7. doi: 10.1073/pnas.78.4.2526.
Weanling Fischer 344 rats received a single intraperitoneal injection of a 1000-fold concentrated preparation of endogenous nontransforming rat retrovirus. Ten days later, the rats were each given a single subcutaneous injection of 3-methylcholanthrene. The rats inoculated with the endogenous rat retrovirus were significantly protected against the development of cancer, whereas uninoculated rats and rats given one of several murine retroviruses or baboon retrovirus were not protected.
断乳期的费希尔344大鼠接受了一次腹腔注射内源性非转化大鼠逆转录病毒的1000倍浓缩制剂。10天后，每只大鼠接受一次皮下注射3-甲基胆蒽。接种内源性大鼠逆转录病毒的大鼠在预防癌症发生方面得到了显著保护，而未接种的大鼠以及接种了几种鼠逆转录病毒或狒狒逆转录病毒之一的大鼠则未得到保护。
