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一项关于三种剂量的ici 35 868用于诱导和维持麻醉的研究。

A study of three doses of ici 35 868 for induction and maintenance of anaesthesia.

作者信息

Major E, Verniquet A J, Waddell T K, Savege T M, Hoffler D E, Aveling W

出版信息

Br J Anaesth. 1981 Mar;53(3):267-72. doi: 10.1093/bja/53.3.267.

DOI:10.1093/bja/53.3.267
PMID:6970586
Abstract

Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes comparable to those reported for other induction agents. Recovery from the effects of the drug was rapid and uneventful.

摘要

比较了三种剂量（1.5、2.0和2.5毫克/千克）的二异丙酚（ICI 35 868）对接受短时间妇科手术的健康女性进行麻醉诱导和维持的效果。麻醉诱导平稳且迅速。心血管变化（呈剂量依赖性）包括动脉压降低和心率增加。这些变化的幅度与其他诱导剂报道的相当。药物作用后的恢复迅速且平稳。

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