Mutagenic and cell transforming activities of 1-chlor-2,4-dinitrobenzene (DNCB) and squaric-acid-dibutylester (SADBE).
作者信息
Strobel R, Röhrborn G
出版信息
Arch Toxicol. 1980 Oct;45(4):307-14. doi: 10.1007/BF00293811.
PMID:7004402
Abstract
In the Salmonella/microsome test, DNCB was mutagenic for TA100, TA1538, and TA98, whereas SADBE did not induce mutations in the test system. The ability of the compounds to transform BHK cells being able to reproduce in semi-solid agar was investigated. DNCB induced a dose-dependent increase in transformed cells, SADBE did not show this effect.
摘要
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