Simon C, Höger P, Toeller W, Kiosz D, Schröder B, Brackebusch H D
Infection. 1982;10 Suppl 2:S79-83. doi: 10.1007/BF01640860.
Chlamydia trachomatis was assayed using McCoy cell culture on vaginal swabs from pregnant women and on conjunctival and nasopharyngeal swabs from newborns. C. trachomatis was found in 23 of 168 pregnant women (8%) and in 15 of 298 newborns (5%). Six newborns developed a typical inclusion conjunctivitis, whereas three infants developed pneumonia caused by C. trachomatis. Of a total of 50 children with conjunctivitis, C. trachomatis was found in six of 22 newborns, in four of 22 infants (2-3 months old) and in none of the older infants and children. Specific antibodies in serum could be demonstrated in most patients by the microimmunofluorescence technique, whereas antibodies against C. trachomatis were only found in a small percentage of the healthy children of various ages. Recommendations are given for the diagnosis of infections caused by C. trachomatis in newborns and infants.
采用 McCoy 细胞培养法对孕妇的阴道拭子以及新生儿的结膜和鼻咽拭子进行沙眼衣原体检测。168 名孕妇中有 23 名（8%）检测出沙眼衣原体，298 名新生儿中有 15 名（5%）检测出沙眼衣原体。6 名新生儿患上典型的包涵体结膜炎，3 名婴儿患上由沙眼衣原体引起的肺炎。在总共 50 名患有结膜炎的儿童中，22 名新生儿中有 6 名检测出沙眼衣原体，22 名婴儿（2 - 3 个月大）中有 4 名检测出沙眼衣原体，年龄较大的婴儿和儿童均未检测出。大多数患者血清中的特异性抗体可通过微量免疫荧光技术检测出来，而不同年龄段的健康儿童中只有一小部分检测出抗沙眼衣原体抗体。文中给出了关于新生儿和婴儿沙眼衣原体感染诊断的建议。
