Edwards J C
Immunobiology. 1982 Apr;161(3-4):227-31. doi: 10.1016/S0171-2985(82)80078-8.
Type A synovial lining cells resemble macrophages in their ultrastructure. Type B lining cells, in contrast, resemble tissue fixed synthetic cells such as fibroblasts. Although cells with intermediate features are well recognised, recent evidence suggests that types A and B cells have different origins. Experiments on mouse radiation chimeras suggest a bone marrow derivation for the type A cells, but not for the type B. Esterase activity, surface Ia, and immunoglobulin receptors have been demonstrated in relation to a proportion of lining cells. It seems reasonable at the present time to consider type A lining cells as belonging to the Mononuclear Phagocyte System.
A型滑膜衬里细胞在超微结构上类似于巨噬细胞。相比之下，B型衬里细胞类似于组织固定的合成细胞，如成纤维细胞。尽管具有中间特征的细胞已得到充分认识，但最近的证据表明，A型和B型细胞有不同的起源。对小鼠辐射嵌合体的实验表明，A型细胞来源于骨髓，而B型细胞并非如此。已证明一定比例的衬里细胞具有酯酶活性、表面Ia和免疫球蛋白受体。目前，将A型衬里细胞视为单核吞噬细胞系统的一部分似乎是合理的。
