Pass M A, McSweeney C S, Reynoldson J A
J Appl Toxicol. 1981 Feb;1(1):38-41. doi: 10.1002/jat.2550010110.
When lantana was given into different regions of the alimentary tract, absorption sufficient to cause intoxication occurred from the stomachs, small intestine and large intestine, but absorption from the small intestine was quantitatively the most important. However, it was shown that the passage of ingesta into the small intestine decreased markedly a few hours after the toxin was given and it is suggested that absorption from all areas of the gastrointestinal tract is important for the progression of the disease. When bile was diverted away from the small intestine, animals were still intoxicated by lantana. This indicates that bile is not important for absorption of lantana toxins. Other experiments indicated that the lantana toxins are transported to the liver mainly in the portal blood.
当马缨丹被注入消化道的不同部位时，从胃、小肠和大肠均发生了足以导致中毒的吸收，但从小肠的吸收在数量上最为重要。然而，研究表明，给予毒素数小时后，食糜进入小肠的过程显著减少，有人提出胃肠道所有部位的吸收对疾病进展都很重要。当胆汁从小肠分流时，动物仍会因马缨丹而中毒。这表明胆汁对马缨丹毒素的吸收并不重要。其他实验表明，马缨丹毒素主要通过门静脉血输送到肝脏。
