• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

离子载体与其他抗菌剂对厌氧菌活性的比较。

Comparison of the activity of ionophores with other antibacterial agents against anaerobes.

作者信息

Watanabe K, Watanabe J, Kuramitsu S, Maruyama H B

出版信息

Antimicrob Agents Chemother. 1981 Apr;19(4):519-25. doi: 10.1128/AAC.19.4.519.

DOI:10.1128/AAC.19.4.519
PMID:7247375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC181469/
Abstract

Representative polyethers of each group in Westley's classification and related ionophore antibiotics were examined for in vitro activity against 25 anaerobic strains. Lasalocid (X-537A) and nigericin were found to have activity comparable in potency to some leading antianaerobe antibiotics, newer cephalosporins and nitroimidazoles, with a different spectrum as revealed by a spectral comparison. A strict relationship between their antianaerobe activity and either their structural features or cation transporting properties was not apparent.

摘要

对韦斯特利分类中每组的代表性聚醚及相关离子载体抗生素进行了检测，以观察其对25株厌氧菌株的体外活性。发现拉沙洛西（X-537A）和尼日利亚菌素的活性在效力上与一些主要的抗厌氧菌抗生素、新型头孢菌素和硝基咪唑相当，光谱比较显示其具有不同的光谱。它们的抗厌氧菌活性与其结构特征或阳离子转运特性之间没有明显的严格关系。

相似文献

1
Comparison of the activity of ionophores with other antibacterial agents against anaerobes.离子载体与其他抗菌剂对厌氧菌活性的比较。
Antimicrob Agents Chemother. 1981 Apr;19(4):519-25. doi: 10.1128/AAC.19.4.519.
2
Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis.通过多样性为导向的半合成拓展聚醚类离子载体抗生素的抗菌选择性。
Nat Chem. 2021 Jan;13(1):47-55. doi: 10.1038/s41557-020-00601-1. Epub 2020 Dec 22.
3
Antimicrobial agents acting against anaerobes.抗厌氧菌的抗菌药物。
J Antimicrob Chemother. 1975 Sep;1(3):273-89. doi: 10.1093/jac/1.3.273.
4
Inhibitory activity of cefotetan and other beta-lactams against anaerobes.
J Antimicrob Chemother. 1983 Jan;11 Suppl:107-15. doi: 10.1093/jac/11.suppl_a.107.
5
The susceptibility of ionophore-resistant Clostridium aminophilum F to other antibiotics.耐离子载体嗜氨基梭菌F对其他抗生素的敏感性。
J Antimicrob Chemother. 2003 Oct;52(4):623-8. doi: 10.1093/jac/dkg398. Epub 2003 Sep 1.
6
In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs.某些抗球虫药物抗支原体作用的体外试验
Vet Microbiol. 1987 Oct;15(1-2):65-70. doi: 10.1016/0378-1135(87)90130-1.
7
Susceptibilities of anaerobic bacteria to N-formimidoyl thienamycin (MK0787) and to other antibiotics.厌氧菌对N-甲酰亚胺基硫霉素（MK0787）及其他抗生素的敏感性。
Antimicrob Agents Chemother. 1982 Jun;21(6):1016-22. doi: 10.1128/AAC.21.6.1016.
8
N-formimidoyl thienamycin (MK0787): in vitro activity against anaerobic bacteria.N-甲酰亚胺基硫霉素（MK0787）：对厌氧菌的体外活性
Antimicrob Agents Chemother. 1982 Jan;21(1):168-9. doi: 10.1128/AAC.21.1.168.
9
Evaluation of the in-vitro antibacterial activity of Sch 34343.Sch 34343的体外抗菌活性评估。
J Antimicrob Chemother. 1985 Jun;15 Suppl C:39-56. doi: 10.1093/jac/15.suppl_c.39.
10
In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria.三抗菌GV104326对革兰氏阳性菌、革兰氏阴性菌和厌氧菌的体外活性。
Antimicrob Agents Chemother. 1994 Oct;38(10):2362-8. doi: 10.1128/AAC.38.10.2362.

引用本文的文献

1
The effects of plant extracts on microbial community structure in a rumen-simulating continuous-culture system as revealed by molecular profiling.分子分析揭示植物提取物对瘤胃模拟连续培养系统中微生物群落结构的影响。
Folia Microbiol (Praha). 2004;49(2):151-5. doi: 10.1007/BF02931391.
2
Antimicrobial growth promoters used in animal feed: effects of less well known antibiotics on gram-positive bacteria.动物饲料中使用的抗菌生长促进剂：鲜为人知的抗生素对革兰氏阳性菌的影响。
Clin Microbiol Rev. 2003 Apr;16(2):175-88. doi: 10.1128/CMR.16.2.175-188.2003.
3
Whey fermentation by anaerobiospirillum succiniciproducens for production of a succinate-based animal feed additive.琥珀酸厌氧螺菌发酵乳清以生产基于琥珀酸的动物饲料添加剂。
Appl Environ Microbiol. 1999 May;65(5):2260-3. doi: 10.1128/AEM.65.5.2260-2263.1999.
4
Biological characterization of cyclothialidine, a new DNA gyrase inhibitor.新型DNA回旋酶抑制剂环噻硫腚的生物学特性
Antimicrob Agents Chemother. 1993 Dec;37(12):2656-61. doi: 10.1128/AAC.37.12.2656.
5
Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives.瘤胃细菌对抗微生物饲料添加剂的敏感性和抗性
Appl Environ Microbiol. 1987 Jul;53(7):1620-5. doi: 10.1128/aem.53.7.1620-1625.1987.
6
Effects of antibacterial agents on in vitro ovine ruminal biotransformation of the hepatotoxic pyrrolizidine alkaloid jacobine.抗菌剂对肝毒性吡咯里西啶生物碱羽扇豆碱体外羊瘤胃生物转化的影响。
Appl Environ Microbiol. 1992 Aug;58(8):2559-64. doi: 10.1128/aem.58.8.2559-2564.1992.

本文引用的文献

1
Biochemistry active substances from microorganisms. IV. Establishment of several in vitro anti-inflammatory probes applicable to microbial broths the effects of non-steroidal anti-inflammatory drugs and antibiotics on them.
Chem Pharm Bull (Tokyo). 1980 Sep;28(9):2553-64. doi: 10.1248/cpb.28.2553.
2
Ro 13-9904/001, a novel potent and long-acting parenteral cephalosporin.Ro 13-9904/001，一种新型强效长效肠胃外注射用头孢菌素。
J Antibiot (Tokyo). 1980 Jul;33(7):783-6. doi: 10.7164/antibiotics.33.783.
3
Metabolic aspects of the secretion of stored compounds from blood platelets. IV. Effects of ionophore X537A on washed platelets.血小板中储存化合物分泌的代谢方面。IV. 离子载体X537A对洗涤后血小板的影响。
Biochim Biophys Acta. 1976 Apr 23;428(2):369-78. doi: 10.1016/0304-4165(76)90044-1.
4
Treatment of anaerobic infections with metronidazole.甲硝唑治疗厌氧菌感染
Antimicrob Agents Chemother. 1975 May;7(5):672-5. doi: 10.1128/AAC.7.5.672.
5
Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud.海洋微生物研究。五、一种从浅海淤泥中分离出的链霉菌产生的新型抗生素——无浆霉素。
J Antibiot (Tokyo). 1976 Oct;29(10):1019-25. doi: 10.7164/antibiotics.29.1019.
6
Susceptibility of anaerobic bacteria to 23 antimicrobial agents.厌氧菌对23种抗菌剂的敏感性。
Antimicrob Agents Chemother. 1976 Oct;10(4):736-52. doi: 10.1128/AAC.10.4.736.
7
Beta-lactamase activity in anaerobic bacteria.厌氧菌中的β-内酰胺酶活性
Antimicrob Agents Chemother. 1976 Jul;10(1):106-11. doi: 10.1128/AAC.10.1.106.
8
Comparative susceptibility of anaerobic bacteria to ticarcillin, cefoxitin, metronidazole, and related antimicrobial agents.厌氧细菌对替卡西林、头孢西丁、甲硝唑及相关抗菌药物的敏感性比较。
Antimicrob Agents Chemother. 1977 Apr;11(4):679-82. doi: 10.1128/AAC.11.4.679.
9
Biological applications of ionophores.离子载体的生物学应用。
Annu Rev Biochem. 1976;45:501-30. doi: 10.1146/annurev.bi.45.070176.002441.
10
Comparative in vitro activity of newer cephalosporins against anaerobic bacteria.新型头孢菌素对厌氧菌的体外比较活性
Antimicrob Agents Chemother. 1978 Nov;14(5):668-71. doi: 10.1128/AAC.14.5.668.