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使用自动血气分析仪测量氧分压。

Oxygen tension measurement using an automatic blood gas analyser.

作者信息

Becket J, Orchard C, Chakrabarti M K, Hall G M, Gillies I D, Bourdillon P J

出版信息

J R Soc Med. 1981 Aug;74(8):595-600. doi: 10.1177/014107688107400808.

Abstract

Two different methods of assessing the reliability of the oxygen electrode of one model of an automatic blood gas analyser (BGA) have been studied. In the first, a single automatic BGA was assessed by using outdated bank blood which was pumped around a small extracorporeal circuit into which known gas mixtures were passed. Oxygen tension was varied between 2 and 16 kPa. In the second, fresh heparinized blood was tonometered with calibrated gases and submitted to the automatic BGA used in the first part of the study and also to three other identical machines. Each of the machines was between 3 and 4 years old.Eighteen different units of blood were used in the first part of the study. The correlation coefficient between the automatic BGA and the Po(2) in the extracorporeal circuit varied between 0.29 and 0.99. 31% of the total of 209 measurements made by the automatic BGA were more than 1.2 kPa from the reference value, 25% of them being between 1.2 and 4.0 kPa from the reference value. In the second part of the study, the correlation coefficient between this automatic BGA and the tonometered blood was 0.96. The correlation coefficients for the 3 other identical BGAs were 0.84, 0.97 and 0.88, indicating that the BGA used in the first part of the study was no worse than any of the others.It is suggested that although clinicians are likely to ignore readings of an automatic BGA that are more than 4.0 kPa from the true value and are likely to repeat the investigation, readings between 1.2 and 4.0 kPa from the true value may adversely affect patient management.

摘要

对某一型号自动血气分析仪(BGA)氧电极的可靠性评估采用了两种不同方法。第一种方法,使用一台自动BGA,通过抽取过期库存血,使其在一个小型体外循环回路中循环,并向该回路通入已知气体混合物来进行评估。氧分压在2至16 kPa之间变化。第二种方法,将新鲜肝素化血液用校准气体进行血气测定,并提交给在研究第一部分中使用的自动BGA以及另外三台相同的仪器。每台仪器使用年限在3至4年。研究第一部分使用了18个不同的血液样本。自动BGA与体外循环回路中氧分压(Po₂)之间的相关系数在0.29至0.99之间。自动BGA进行的209次测量中,有31%与参考值相差超过1.2 kPa,其中25%与参考值相差在1.2至4.0 kPa之间。在研究的第二部分,该自动BGA与经血气测定的血液之间的相关系数为0.96。其他三台相同BGA的相关系数分别为0.84、0.97和0.88,这表明在研究第一部分中使用的BGA并不比其他任何一台差。有人认为,尽管临床医生可能会忽略自动BGA中与真实值相差超过4.0 kPa的读数,并可能会重复进行检测,但与真实值相差在1.2至4.0 kPa之间的读数可能会对患者的治疗管理产生不利影响。

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