从霍乱弧菌中分离出的R突变体的脂多糖。
Lipopolysaccharides of R mutants isolated from Vibria cholerae.
作者信息
Hisatsune K, Kondo S
出版信息
Biochem J. 1980 Jan 1;185(1):77-81. doi: 10.1042/bj1850077.
Abstract
The chemical and serological properties of lipopolysaccharides isolated from the S form and from the R form of cholera vibrios were compared. It was found that the S-R mutation of cholera vibrios involves total elimination of the two component amino sugars of S-form lipopolysaccharides, i.e. quinovosamine and perosamine. This elimination resulted in the loss of O-specificity of S-form lipopolysaccharides and concomitant appearance of strong serological cross-reactivity, in the passive-haemolysis-inhibition test, among R-form lipopolysaccharides regardless of the serotypes (Inaba and Ogawa) of their S parent strains.
摘要
比较了从霍乱弧菌S型和R型分离出的脂多糖的化学和血清学特性。发现霍乱弧菌的S-R突变涉及S型脂多糖的两种组成氨基糖，即奎诺糖胺和过氧胺的完全消除。这种消除导致S型脂多糖的O特异性丧失，并在被动溶血抑制试验中，R型脂多糖之间出现强烈的血清学交叉反应，而不论其S亲本菌株的血清型（稻叶型和小川型）如何。
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