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尿有机酸的气相色谱分析法。I. 155种代谢重要化合物的保留指数

Gas-chromatographic method of analysis for urinary organic acids. I. Retention indices of 155 metabolically important compounds.

作者信息

Tanaka K, Hine D G, West-Dull A, Lynn T B

出版信息

Clin Chem. 1980 Dec;26(13):1839-46.

PMID:7438429
Abstract

Gas-chromatographic retention indices are given, in terms of methylene units, for 155 metabolically important compounds (mostly organic acids) as trimethylsilyl derivatives on 10% OV-1 and 10% OV-17 columns. Comprehensive references on metabolic diseases that can be diagnosed by detection of these metabolites are cross-indexed to facilitate the use of the methylene-unit list. With the data presented here, it is now possible to diagnose more than 25 well-defined organic acidurias by use of gas chromatography alone.

摘要

给出了155种代谢重要化合物(主要是有机酸)作为三甲基硅烷基衍生物在10% OV - 1和10% OV - 17柱上以亚甲基单位表示的气相色谱保留指数。对可通过检测这些代谢物进行诊断的代谢疾病的综合参考文献进行了交叉索引,以方便使用亚甲基单位列表。根据此处提供的数据,现在仅使用气相色谱就有可能诊断出超过25种明确的有机酸尿症。

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Gas-chromatographic method of analysis for urinary organic acids. I. Retention indices of 155 metabolically important compounds.尿有机酸的气相色谱分析法。I. 155种代谢重要化合物的保留指数
Clin Chem. 1980 Dec;26(13):1839-46.
2
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[Methodology in the study of organic acids in children].[儿童有机酸研究中的方法学]
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Seven years of experience with selective screening for organic acidurias.有机酸尿症选择性筛查的七年经验
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