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1
A ribosomal frameshifting error during translation of the argI mRNA of Escherichia coli.大肠杆菌argI信使核糖核酸（mRNA）翻译过程中的核糖体移码错误。
Mol Gen Genet. 1994 May 25;243(4):434-41. doi: 10.1007/BF00280474.
2
Analyses of frameshifting at UUU-pyrimidine sites.对UUU-嘧啶位点移码的分析。
Nucleic Acids Res. 1997 May 15;25(10):2005-11. doi: 10.1093/nar/25.10.2005.
3
Increased ribosomal accuracy increases a programmed translational frameshift in Escherichia coli.核糖体准确性的提高会增加大肠杆菌中一种程序性翻译移码。
Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2315-9. doi: 10.1073/pnas.90.6.2315.
4
Effects of GUG and AUG initiation codons on the expression of lacZ in Escherichia coli.GUG和AUG起始密码子对大肠杆菌中lacZ表达的影响。
FEBS Lett. 1986 Mar 3;197(1-2):315-20. doi: 10.1016/0014-5793(86)80349-0.
5
Frameshifting at the internal stop codon within the mRNA for bacterial release factor-2 on eukaryotic ribosomes.真核生物核糖体上细菌释放因子-2的信使核糖核酸（mRNA）内的内部终止密码子处的移码。
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DNA sequences required for translational frameshifting in production of the transposase encoded by IS1.IS1编码的转座酶产生过程中翻译移码所需的DNA序列。
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Misreading of the argI message in Escherichia coli.
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CCC.UGA: a new site of ribosomal frameshifting in Escherichia coli.CCC.UGA：大肠杆菌中核糖体移码的一个新位点。
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10
Translational accuracy during exponential, postdiauxic, and stationary growth phases in Saccharomyces cerevisiae.酿酒酵母在指数生长期、二次生长后期和稳定期的翻译准确性。
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Transduction of linked genetic characters of the host by bacteriophage P1.噬菌体P1对宿主连锁遗传性状的转导
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2
On the directional specificity of ribosome frameshifting at a "hungry" codon.关于核糖体在“饥饿”密码子处移码的方向特异性。
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3
Frameshifting in the expression of the E. coli trpR gene occurs by the bypassing of a segment of its coding sequence.大肠杆菌trpR基因表达中的移码现象是通过跳过其编码序列的一段来发生的。
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4
Mistranslation in cells infected with the bacteriophage MS2: direct evidence of Lys for Asn substitution.感染噬菌体MS2的细胞中的错译：赖氨酸替代天冬酰胺的直接证据。
Mol Gen Genet. 1980;180(2):275-81. doi: 10.1007/BF00425839.
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Mechanism of ribosome frameshifting during translation of the genetic code.遗传密码翻译过程中核糖体移码的机制。
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The tac promoter: a functional hybrid derived from the trp and lac promoters.Tac启动子：一种源自色氨酸启动子和乳糖启动子的功能性杂种启动子。
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7
Beta-galactosidase gene fusions for analyzing gene expression in escherichia coli and yeast.用于分析大肠杆菌和酵母中基因表达的β-半乳糖苷酶基因融合体
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8
Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes.大肠杆菌转移RNA丰度与其蛋白质基因中相应密码子出现情况之间的相关性。
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Isolation and characterization of frameshift mutations in the lac operon.
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Low activity of -galactosidase in frameshift mutants of Escherichia coli.大肠杆菌移码突变体中β-半乳糖苷酶活性较低。
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大肠杆菌argI信使核糖核酸（mRNA）翻译过程中的核糖体移码错误。

A ribosomal frameshifting error during translation of the argI mRNA of Escherichia coli.

作者信息

Fu C, Parker J

机构信息

Department of Microbiology, Southern Illinois University, Carbondale 62901.

出版信息

Mol Gen Genet. 1994 May 25;243(4):434-41. doi: 10.1007/BF00280474.

DOI:10.1007/BF00280474
PMID:7515462
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7087753/
Abstract

Using fusions between the Escherichia coli genes argI and lacZ, it has been demonstrated that ribosomal frameshifting occurs at a frequency of between 3% and 16% within the argI mRNA, soon after the initiation codon. The frameshift involves a phenylalanyl-tRNA shifting into the +1 frame at the sequence UUU-U/C. The shift does not occur if the in-frame phenylalanine codon UUU is replaced by UUC. The level of frameshifting is higher in dense cultures and is not dependent on phenylalanine starvation. In the wild-type argI gene this frameshifting event would be an error, leading to a truncated, non-functional protein. Therefore, it is unlike the numerous examples of required frameshifting events that have been described in other genes.

摘要

利用大肠杆菌基因argI和lacZ之间的融合，已证明核糖体移码在起始密码子后不久的argI mRNA内以3%至16%的频率发生。移码涉及苯丙氨酰-tRNA在UUU-U/C序列处移至+1读框。如果框内苯丙氨酸密码子UUU被UUC取代，则不会发生移码。移码水平在高密度培养物中更高，且不依赖于苯丙氨酸饥饿。在野生型argI基因中，这种移码事件将是一个错误，导致产生截短的、无功能的蛋白质。因此，它不同于其他基因中描述的众多必需移码事件的例子。