测序分析揭示了人型支原体gyrB区域独特的基因组织。
Sequencing analysis reveals a unique gene organization in the gyrB region of Mycoplasma hominis.
作者信息
Ladefoged S A, Christiansen G
机构信息
Institute of Medical Microbiology, University of Aarhus, Denmark.
出版信息
J Bacteriol. 1994 Sep;176(18):5835-42. doi: 10.1128/jb.176.18.5835-5842.1994.
Abstract
The homolog of the gyrB gene, which has been reported to be present in the vicinity of the initiation site of replication in bacteria, was mapped on the Mycoplasma hominis genome, and the region was subsequently sequenced. Five open reading frames were identified flanking the gyrB gene, one of which showed similarity to that which encodes the LicA protein of Haemophilus influenzae. The organization of the genes in the region showed no resemblance to that in the corresponding regions of other bacteria sequenced so far. The gyrA gene was mapped 35 kb downstream from the gyrB gene.
摘要
据报道，细菌复制起始位点附近存在gyrB基因的同源物，该同源物被定位在人型支原体基因组上，随后对该区域进行了测序。在gyrB基因两侧鉴定出五个开放阅读框，其中一个与编码流感嗜血杆菌LicA蛋白的序列相似。该区域的基因组织与迄今为止测序的其他细菌的相应区域不同。gyrA基因位于gyrB基因下游35 kb处。
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